Chapter 8- Tablets Flashcards
Solid dosage forms prepared by compression with the aid of suitable pharmaceutical excipients
Tablets
Vary in: size, shape, weight, hardness, thickness, disintegration and dissolution characteristics and in other aspects, depending on their intended use and method of manufacture
Tablets
For oral administration of drugs, others sublingually, buccally or vaginally, with features mist applicable to the routes of administration
Tablets
Some are scored allow to be easily broken into two or more parts
Tablets
Characteristics of Ideal Tablets
- Free of defects: chips, cracks, discoloration and contamination
- Strength to withstand mechanical stresses of production
- Stable
- Release medicinal agents in a predictable and reproducible manner
No special coating manufactured with tablet machine with great pressure or compacting the powdered or granulated tableting material
Compressed tablets (CT)
Contain pharmaceutical adjuncts: diluents or filters, binders or adhesives, disintegrants, antidiarrheals, etc
Compressed tablets (CT)
Prepared by: subjecting the fill material to more than a single compression
Multiple compressed tablets (MCT)
Result: multiple layer or a tablet within a tablet, inner tablet (core) and outer portion (shell)
Multiple compressed tablets (MCT)
Compressed tablets with colored or uncoloured sugar layer
Sugarcoated tablets (SCT)
Protects the enclosed drug from the environment
Sugarcoated tablets (SCT)
Provides a barrier to objectionable taste of odor
Sugarcoated tablets (SCT)
Enhances the appearance
Sugarcoated tablets (SCT)