Chapter 8: Gene Expression

Question 1

What is totipotency?

Answer 1

The ability of that single cell to divide and produce all of the differentiated cells in an organism

Question 2

Places gene expression can be controlled?

Answer 2

1. ) Transcriptional control
2. ) RNA processing
3. ) RNA can be prevented from leaving the nucleus
4. ) Made inactive doesn’t translate
5. ) Make protein active or inactive

Question 3

How many transcription factors are there in the human genome?

Answer 3

1500. They interact with base pairs in the major groove.

Question 4

Where to TF contact DNA?

Answer 4

They touch the bases that stick out in the major groove. They bond non-colvalntly (hydrogen bonds, electrostatic interactions) int–causes no disruption in the base pair or DNA.

The binding makes sense because we want the TFs to find what they are regulating and stay put

Question 5

Are many TF’s dimers?

Answer 5

yes

Question 6

How does prokaryote gene regulation work?

Answer 6

They can be positive the promote transcription (recruit RNA polymerase) called ACTIVATORS

They can repress transcription by binding to regions in DNA that are important for transcription. There repressor are called operators

Question 7

How many of e coli’s genes are expressed at one time?

Answer 7

500. It e. coli has a total of 4500. The other 4000 are used when needed to respond to environmental changes. Various operons are induced when needed and repressed when not needed.

Question 8

What is the name of the organization of genes in the same metabolic pathway?

Answer 8

operons. Operons might be a single mRNA