Chapter 8 Cell Communication Flashcards
Apoptosis
Programmed cell death
Autocrine signal
Signal sent and received by the same cell
Autoinducer
Signaling molecule secreted by bacteria to communicate with others
Cell-surface receptor
Protein transmitting signal from outside to inside the cell
Chemical synapse
Small space between nerve cells where neurotransmitters function
Cyclic AMP (cAMP)
Second messenger derived from ATP
Cyclic AMP-dependent kinase (PKA)
Kinase activated by binding to cAMP
Diacylglycerol (DAG)
Cleavage product of PIP2 used for signaling within the plasma membrane
Dimer
Chemical compound formed by two molecules joining
Endocrine cell
Cell releasing ligands involved in endocrine signaling (hormones)
Endocrine signal
Long-distance signal delivered by ligands (hormones) in the circulatory system
Extracellular domain
Region of a cell-surface receptor located on the cell surface
G-protein-coupled receptor
Cell-surface receptor activating G-proteins to transmit signals
Inhibitor
Molecule binding and preventing a protein (usually enzyme) from functioning
Inositol phospholipid (PIP2)
Lipid converted into a second messenger
Inositol triphosphate (IP3)
Cleavage product of PIP2 used for signaling within the cell
Intercellular signaling
Communication between cells
Internal receptor
Receptor protein located in the cell’s cytosol and binds to ligands
Intracellular signaling
Communication within cells
Ion channel-linked receptor
Cell-surface receptor forming a plasma membrane channel opening upon ligand binding
Kinase
Enzyme transferring a phosphate group from ATP to another molecule
Ligand
Molecule produced by a signaling cell that binds with a specific receptor
Neurotransmitter
Chemical ligand carrying a signal from one nerve cell to another
Paracrine signal
Signal between nearby cells delivered by ligands in the liquid medium
Phosphatase
Enzyme removing the phosphate group from a phosphorylated molecule
Quorum sensing
Method of cellular communication informing bacteria of other bacteria’s abundance
Receptor
Protein in or on a target cell that binds to ligands
Second messenger
Small, non-protein molecule propagating a signal within the cell after receptor activation
Signal transduction
Propagation of the signal through the cell’s cytoplasm (and sometimes nucleus)
Signaling pathway
Chain of events propagating the signal from the plasma membrane to produce a response