Chapter 8: Biological Membranes Flashcards
Cell Plasma membrane.
A semi permeable barrier, it chooses which particles can enter and leave the cell at any point in time. This selectivity is mediated not only by the various channels and carriers that poke holes in their brain, but also by the membrane itself.
Glycoprotein coat
Carbohydrates associated with membrane bound proteins create a glycoprotein coat. The cell wall of plants, bacteria and fungi contain higher levels of carbohydrates.
Lipid rafts.
Collection of similar lipids, with or without associated proteins that serve as attachment points for other biomolecules. These rafts often serve roles in signaling.
Membrane dynamics.
It is a semi solid and in constant state of flux. Fossil lipids move rapidly in the plane of their membrane through simple diffusion.
Flippases
Assist in the transition or flip between layers.
Fatty acids and triglycerides.
Fatty acids are carboxylic acids that contain a hydrocarbon chain and terminal carboxyl group. Triglycerides also refer to as triglycerides or storage lipids involved in human metabolic process. They contain three fatty acid chains esterified to a glycerol molecule.
Phospholipids
They have a phosphate group, a polar head group joins the nonpolar tails, forming a glycerophospholipid, commonly called phospholipid.
Sphingolipids
They do not contain glycerol but have a sphingosine backbone. Classes of Sphingolipids and their hydrophilic groups include ceramide, sphingomyelin, cerebrosides, and gangliosides.
Cholesterol and steroids.
Cholesterol not only regulates membrane fluidity, but it also is necessary in the synthesis of steroids, which are derived from cholesterol. Membrane stability is derived from interactions with both the hydrophilic and hydrophobic regions that make up the phospholipid bilayer. While cholesterol stabilizes adjacent phospholipids, it also occupies space between them. This prevents the formation of crystal structures in the membrane, increasing fluidity at lower temperatures. It decreases fluidity and it helps hold the membrane intact. Cholesterol composes about 20% of the cell membrane by mole fraction by mass.
Waxes
Extremely hydrophobic but are sometimes found in the saline brains of plants. A wax is composed of a long chain fatty acid and a long chain alcohol, which contributes to the high melting point of these substances. Waxes can provide both stability and rigidity within the nonpolar tail region only.
Transmembrane proteins.
Passed completely through the lipid bilayer.
Embedded proteins.
Are associated with only the interior or exterior surface of the cell membrane.
Integral proteins.
Together, transmembrane and embedded proteins are considered integral proteins because of their association with the interior of the plasma membrane.
Membrane associated (Peripheral) Proteins.
Maybe bound through electrostatic interactions with the lipid bilayer, especially a lipid raft.
Carbohydrates
Are generally attached to protein molecules on the extracellular surface of the cell. Interactions between glycoproteins and water and can form a coat around the cell. It can act as signaling and recognition molecules.