Chapter 8 Flashcards
Mitosis and Meiosis
Cell Reproduction
division of one cell into two daughter cells
Reasons for cell reproduction
- cell replacement
- growth
-reproduction
Chromatin
uncondensed chromosomes, made up of histone and DNA
Chromosome
Long strands of DNA loosely packed in the nucleus
DNA Packing
the process by which a cell’s long DNA molecule is tightly coiled and wrapped around proteins called histones, forming a compact structure called chromatin, allowing it to fit within the small space of the cell nucleus
Nucleosome
when chromatin wraps around a histone to form almost a bead on a friendship bracelet.
Centromere
the “waist” at which sister chromatids are attached
Sister Chromatids
Duplicated chromosomes that are still connected
Cell Cycle
Composed of two phases interphase and mitotic
Interphase
90% of cell’s life and has three phases: Gap 1, Synthesis phases, Gap 2
Gap One
during this time, cells grow, organelles grow in numbers, and everything else functions normally
Synthesis Phase
When DNA is replicated
Gap Two
Proofreading of DNA, more growth in preparation for cell division
Apoptosis
cell-suicide that allows the cell’s parts to be reused
Mitosis
the production of two genetically identical daughter cells
PMAT
phases of mitosis: prophase, (prometaphase), metaphase, anaphase, telophase
Prophase
when sister chromatids condense, the nucleic membrane dissolves, and centrioles start to produce spindle fibers made of microtubules
Metaphase
chromosomes align in the middle of cell and the spindle fibers attach to the centromeres (but not al of them)
Anaphase
when the spindle fibers start to contract or grow and separates the sister chromatids and pushes the cell apart, creating a cleavage furrow
Telophase
nucleic membrane forms to form two daughter nuclei and spindle fibers dissolve, cleavage furrow deepens
Cytokinesis
the physical process of cell division, which divides the cytoplasm of a parental cell into two daughter cells
Cytokinesis in animal cells
a ring of microfilaments just under the plasma membrane contract, effectively pinching the cell into two
Cytokinesis in plant cells
since the cell wall prevents a cleavage furrow, vesicles of cell wall are deposited into the middle and form a cell plate until it connects to the cell wall
Cancer
tumors that grow due to mutations that cause unrestricted cell growth
Malignant tumor
a tumor that travels from its origin
Benign tumor
a tumor that grows in one spot
treatments for cancer
chemotherapy, surgery, radiation, drugs
Homologues
chromosomes that code for the same trait but different alleles
Somatic cells
body cells
Germ cells /gametes
reproductive cells
Autosomes
homologues that code for something in both genders
Sex Chromosomes
XY chromosomes that determine gender (XX=girl, XY=boy)
Metastasize
when cancerous cells break away from its origin and spread
Karyotype
a visual representation of one’s chromosomes in number order
Haploids
one full set of chromosomes (n)
Diploid
two full sets of chromosomes (2n)
Ploidy
the number of sets of chromosomes (xn)
Fertilization
when an egg (or female gamete) meets a sperm (or male gamete) and becomes a zygote
Zygote
The fertilized egg
Meiosis
the reproduction of sex cells
Prophase I
Nuclear envelope dissolves and spindle fibers start to form
Metaphase I
The homologous pairs align in the middle and spindle fibers attach to the pairs. homologous sister chromatids fuse together with specific gene alignment through special proteins, and crossing over occurs
Anaphase I
when the homologous pairs separate
Telophase I
chromatids move to poles of the cells and a nuclear envelope form
Cytokinesis I
two haploid cells form
Meiosis II
Splitting of sister chromatids
Prophase II
spindle forms and nuclear envelope forms
Metaphase II
Sister chromatids align in the middle and spindle fibers attach
Anaphase II
Sister chromatids are separated
Telophase II and Cytokinesis II
four new, unique cells form
Causes of genetic variation
- independent assortment
- cross-over
- non-disjunction
Independent assortment
how the homologous sister chromatids align during Metaphase I
crossing over
when homologous pairs of chromosomes align through special proteins and gene alignment allowing alleles to switch and new genetically unique chromosomes form
Nondisjunction
When a sister chromatid or homologous pair doesn’t separate during one of the anaphases, causing one extra or less chromosome which can lead to mutations such as Down syndrome
Down syndrome
Trisomy 21, three 21st chromosomes that cause stunted growth, and other complications
Tetrad
the fused homologous sister chromatids
Phenotype
the variation of traits within another trait (genotype)
ex//different shades of brown eyes