Chapter 70 - Protein Metabolism Flashcards
Amount of “obligatory loss of protein”
20 to 30 grams per day
TO BE ON THE SAFE SIDE, minimum protein intake recommended
60 to 75 grams per day
Protein linkages
- peptide bonds
- hydrogen bonding
- disulfide bonds
Normal conc. of AA in blood
35 to 65 mg/dl
Rapid AA turnover rate - AA NEVER accumulate in blood
Time of
(1) protein digestion and absorption
(2) AA clearance after entering blood
(1) 2-3 hrs
(2) 5 to 10 minutes
Movement of AA in and out cell membranes
Active transport or facilitated transport using carrier proteins
Plasma proteins
- albumin
- globulins
- fibrinogen - blood coagulation
Rate of plasma protein production in liver
30g/day
labile protein storage medium that function as a readily available source of amino acids
plasma proteins
The most effective therapy for severe, acute whole-body protein deficiency
(reversible equilibrium between plasma proteins and tissue proteins)
Intravenous transfusion of plasma protein
Enzyme responsible for initiating most deamination (especially in liver)
aminotransferases
Amount of protein degradation during starvation
125 grams daily
Hormones that increase protein synthesis
*Growth hormone
*Insulin
*Testosterone
*Estrogen (minimal effect)
Hormones that increase breakdown of most tissue protein
*Glucocorticoids (decrease tissue protein and increase liver protein, plasma protein, and AA)