Chapter 7 - Musculoskeletal (Cut off for Exam 1) Flashcards
Musculoskeletal Injuries
- Arises muscles, joints, bones, and connective tissues
- Can be acute from things like sport injuries (tendonitis, sprains, strains) or exacerbated conditions (osteoarthritis)
- Chronic: pain lasting 3+ months
- Acute: pain lasting < 4 weeks
- 100 million+ adults battle chronic pain in US
Tendons
Connect bones to muscles, usually stretch and twist, rarely rupture, damaged with hyper extended or overused
Ligaments
- Connect bones to bones,
- Usually stretch and twist, rarely rupture, damaged with hyper extended or overused
- More commonly tear or rupture than tendons
Synovial Bursae
- Fluid-filled sac between joint spaces
- Lubrication and cushioning
Catilage
-Protective pads between bones in joints and spine
Skeletal/Striated Muscle
- Responsible for contractions
- Houses pain receptors which are stimulated from overuse or injury
Somatic Pain
- Pain impulse from peripheral nocireceptors to CNS by nerve fibers
- Commonly myofascial (muscle strain) or musculoskeletal (arthritis)
- Mediated by mechanoreceptor and chemoreceptor
Inflammatory Response
- Edema
- Erythema
- Hyperalgesia
Muscle Injury Categories
- Delayed-onset muscle soreness, overexertion (can last days, peaks in 24-48 hours)
- Myalgia (systemic infections, chronic disease, medications)
- Strains (injury to muscle or tendon from strange contraction while lengthening)
- Tendonitis (inflammation of tendon from acute injury or chronic/repetitive movements)
- Bursitis (inflammation of bursa from joint injury or infection
- Sprains (common problem with ligaments, three classes
Grade I Sprain
Excessive Stretching
Grade II Sprain
Partial Tear
Grade III Sprain
Complete Tear
Low Back Pain
- 5th most likely reason for physician visit
- Many risk factors
- Can have serious causes
- Chronic if 3 months or more
Osteoarthritis
- Gradual softening and destruction of cartilage between bones
- Caused by genetic, metabolic, and environmental factors
Musculoskeletal Clinical Presentation
- Pain = common symptom of all categories
- If limited function of joint, likely a grade II/III sprain
- Carpal tunnel - lowered ability to feel hot/cold, false feeling of swelling, weak hands, tendency to drop things
- Osteoarthritis - limits ADLs, pain often referred in proximal muscles due to changed gait or activity
- Low back pain - nerve pain, sharp pain down one or both legs, limits ability to bend, move, sit, or walk
Musculoskeletal Treatment Based on Severity
- Acute - alarm system to injury from trauma, disease, muscle spasm, or inflammation
- Chronic - requires PCP assessment before treatment
Musculoskeletal Treatment Goals
- Decreased intensity of pain
- Decreased duration of pain
- Restoring function to affected area
- Preventing re-injury and disability
- Preventing acute pain from becoming chronic pain
Musculoskeletal General Treatment
- Similar symptoms so similar self-treatment
- Nonpharmacologic: RICE (rest, ice, compression, elevation)
- Pharmacologic: Non-Rx oral analgesics and/or topical analgesics for first 1-3 days
- Same for acute low back pain
- Chronic back pain requires medical assessment
- Osteoarthritis - lifestyle changes and use of analgesic (can be a non-Rx), self-treat after diagnosis
Musculoskeletal Nonpharmacologic
- Warm up and stretch before physical activity, proper hydration, proper footwear to prevent sport injury
- Muscle cramps - stretching, massaging, and immediate rest
- Electrolyte depletion - oral supplementation and fluids
- RICE: promotes healing and reduces swelling and inflammation from muscle/joint injuries
- Don’t apply ice/heat directly to skin and for more than 15-20 minutes at a time, max of 3-4 times per day
- Heat therapy for noninflammatory injury including acute low back pain but NOT osteoarthritis
- Remove adhesions immediately if you experience burning, itching, discomfort, etc.
- TENS - approved for pain by alteration of pain transmission and increased endorphin production (Don’t use if preggo, pacemaker, or a child)
- Proper posture, ergonomic structure use, better-fitting shoes, acupunture, chiropractics, heat therapy, lifestyle changes, and traction massage are also commonly used
Musculoskeletal Pharmacologic Options
- Systemic Analgesics
- Topical analgesics
- Counterirritants
Musculoskeletal Systemic Analgesics
- NSAIDs and APAP are common non-Rx
- Limit to 10 days of use
- Seek medical attention if pain lasts longer than this
- APAP - preferred 1st line for osteoarthritis
- Recommend topical NSAIDs rather than systemic for chronic use due to severe and prevalent SE (use PPI for chronic use)
Musculoskeletal Topical Products
- Local analgesic, anesthetic, antipruritic, and/or counterirritant effects
- Approved for minor to moderate aches and pains of muscles and joints
- Adjuncts to nonpharmacologic/pharmacologic therapies
Counterirritants
- Produce less severe pain to counter a more intense pain
- Pain relief from nerve stimulation
- Produces mild, local inflammatory reaction which decreases perceived pain of actual injury
- Safe to use in adults and kids 2+ y.o.
- Temporary relief for minor to moderate aches and sprains
- Seek medical attention if burning or blistering occurs
Trolamine Salicylate
- Topical analgesic
- Decreases synovial fluid salicylate concentrations lower than aspirin
- Recommended for adults and kids 2+ y.o. is 10-15% 3-4 times per day
- No efficacy studies for topical
- Same CI as salicylates, can be used for hand osteoarthritis
Topical NSAIDs
- Topical analgesic
- Not currently available non-Rx in US
- If injury close to skin surface, same benefits as oral NSAID without SE
- Approved for chronic osteoarthritis use
Musculoskeletal Combination Products
- Don’t combine drugs from the same category usually
- Only do so unless the combination is safer and more effective
- Often add to counterirritants together as long as they’re in different groups
- Counterirritants + Skin protectants don’t go together (counterproductive)
Musculoskeletal Special Populations
- No variability in different ages and races
- Avoid in kids < 2 y.o.
- Use caution in those too young to communicate SE they are experiencing effectively
- Most medications opt for a minimal age of 12 or 18 y.o.
- Common in preggo, but may have risks due to lack of categorization (see PCP first)
- Topical camphor - preggo compatible (low risk)
- Topical salicylates should be avoided in the 3rd trimester due to systemic absorption risk
Musculoskeletal Patient Factors
- Consider patient’s medical history and conditions
- Topicals as adjunct or substitutions of oral medications
- Category I counterirritant should be recommended at lowest effective concentration
Musculoskeletal Patient Preferences
- Dosage form, ease of use, cost, and odor can effect selection
- Ointment increases absorption but are greasy and usually disliked by patients
- Rub in topical products (besides patches and solutions)
Musculoskeletal Complementary Therapies
- Glucosamine and chondroitin - most common supplement for osteoarthritis
- Showed no significant reduction of pain and increase in function of joints
- Not recommended for hip/knee osteoarthritis
Assessment of MS Injuries
- Note medications, past medications, and preferences
- Try to qualify and quantify pain (SCHOLAR-MAC)
- Numerical pain scales help (Mild: 1-3, Moderate: 4-6, Severe: 7-10, may need medical intervention)
- Intervene if patient chronically uses non-Rx analgesics
- Offer education about risks of inadequate treatment and medication overuse
MS Counseling
- Tell them dosage, admin. instructions, interactions, self-monitoring techniques
- In acute pain, administer non-Rx analgesics early and taper off as pain severity allows
- Tell PCP about new or worsening pains
MS Evaluation
- Primary indicator is the patient’s perception of pain relief
- If pain continues or worsens after 7 days, refer them for further evaluation
- Lack of return often means successful treatment
- Those who return with continued swelling, pain, or inflammation - refer for medical evaluation
- Continued pain could indicate a chronic, potentially debilitating, condition
MS Exclusions
- Severe pain
- Pain that lasts > 10 days
- Pain that continues > 7 days after treatment with a topical analgesic
- Increased intensity or change in character of pain
- Pelvic or abdominal pain
- N/V, fever, or other signs of systemic infections or disorders
- Deformed joint, abnormal movement, limb weakness, numbness, suspected fracture
- Pregnancy
- <2 y.o.
- Back pain AND loss of bowel/bladder control
Methyl Salicylate
-Rubefacient
-Causes vasodilation of cutaneous vasculature which promotes reactive hyperemia, inhibits central/peripheral prostaglandin synthesis
-Hot effect
-Localized and systemic reactions (salicylate toxicity)
-Heat increases absorption
-Do not use in children
-Use caution in patients on anticoagulants
EX: Salonpas, Bengay, Icy Hot
Camphor
- Group B
- Cooling sensation
- Depresses cutaneous receptors and at high concentrations stimulates nerve endings in the skin, induces relief of pain by marking deeper visceral pain
- CNS toxicity if ingested which can lead to N/V, seizures, dizziness, headache, delirium, coma, and death
Menthol
- Group B
- Cooling sensation
- <1%: depresses cutaneous receptor response (anesthetic)
- > 1.25%: stimulates cutaneous receptor response (counterirritant)
- Triggers TRPM8 receptor that causes cold sensation that travels along pathway similar to somatic pain sensations from affected muscle or joint
- Feel coolness followed by warmth
- ADR: irritation, rash, burning, swelling
- Ex: Aspercreme, Bengay, Icy Hot, Mineral Ice
Methyl Nicotinate
- MOA: vasodilation and elevation of skin temperature
- ADE: Decreased BP, decreased HR, syncope
Capsicum Preparation
- Group D for acute and chronic pain
- Major ingredient of hot chili peppers
- MOA: Stimulates TRPV1 and depletes of substance P which causes irritation
- Decreases pain but not inflammation
- In 2 weeks pain starts to be relieved, but can take 4-6 weeks to fully take effect
- Must continually use 3-4 times a day