Chapter 7: metabolism Flashcards

1
Q

Metabolism

A

The sum of all the chemical reactions that go on in living cells

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2
Q

Energy

A

The capacity of doing work, stored in food
stored as chemical bonds

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3
Q

How does the body obtain energy from food

A

food provides fuel through a series of reactions that release energies from chemical bonds
bonds break, release energy water and waste

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4
Q

The liver

A

metabolizes, packages, stores, or ships them out for use by other organs and detoxifies other organs

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5
Q

The liver and Carbs

A

-Converts things to glucose
-makes and stores glycogen
-breaks down glycogen and releases glucose
-makes glucose from some amino acids and glycerol when needed
-converts excess glucose to fatty acids

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6
Q

The liver and Proteins

A

-manufactures nonessential amino acids that are in short supplu
-takes certain extra amino acids out of circulation and turns them into glucose or fatty acids
- removes amonia from the blood for excretion
-Makes nitrogen containing compounds
-makes transport and blood proteins

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7
Q

The liver and lipids

A

-builds and breaks down triglycerides, phospholipids and cholesterol as needed
-breaks down. fatty acids for energy when needed
-packages extra lipids in lipoproteins for transport to other body organs
-manufactures bile to send to the galbladder for use of fat digestion
- makes ketone bodies when necessary

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8
Q

Liver’s other functions

A

detoxifies alcohol, other drugs, and poisons, prepares waste products for excretion
-helps dismantle old red blood cells and captures iron for recycling
-stores most vitamins and many minerals
-converts vitamin D into a =n intermediate, metabolic form

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9
Q

Anabolism

A

Building reactions like making glycogen. they require energy

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10
Q

Catabolism

A

The breakdown reactions
making glucose from glycogen reactions release energy to the body

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11
Q

Chemical reactions in the bodyThe transfer of energy in reactions

A

ATP

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12
Q

Chemical reactions in the body

A

powers all the activities of living cells

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13
Q

ATP

A

High energy storage compound that captures some of the energy from catabolism conains 3 phosphate groups whos negative charges make them vulnerable to hydrolysis. When the phosphate bonds are broken they release energy that was captured from catabolism

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14
Q

Coupled reactions

A

the body uses ATP to transfer the energy from catabolic reactions to power anabolic reactions

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15
Q

The transfer of energy in reactions

A

-energy is captures in the high-energy storage compound, ATP
-Negative charges of phosphate groups are vulnerable to hydrolysis
- cleaving P groups releases energy

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16
Q

Enzymes

A

Almost always required
-facilitate reactions
-remain unchanges

17
Q

Coenzyme

A

-complex, organic molecules
-not proteins
-associate with enzymes
-required for enzymes to function
(some vitamin B

18
Q

Digestion (macronutrients are broken down)

A

Carbohydrates
-Glucose
Fats
-Glycerol and fatty acids
Proteins
-Amino acids
Catabolism is the further breakdown into atoms

19
Q

Metabolic pathways

A

Glucose, glycerol, fatty acids and amino acids all take different metabolic pathways

20
Q

Pyruvate

A

3 carbon structure
Can be used to make glucose

21
Q

Acetyl CoA

A

2 carbons and coenzyme CoA
cannot be used to make glucose

22
Q

Fatty acids

A

Converted to acetyl CoA and therefore cannot make glucose

23
Q

Amino acids and glycerol

A

Can be converted to pyruvate and therefore can provide glucose for the body

24
Q

TCA cycle

A

-Tricarboxylic acid cycle, also called the citric acid cycle or the krebs cycle
-all energy-yielding nutrients can enter this pathway
-acetyl coa reacts with 4-c molecules
- each turn of TCA cycle releases 8 electrons

25
Q

Electron Transport Chain

A

-The final pathway in energy metabolism that transports electrons from hydrogen to oxygen
- captures about half the energy released by breaking C-C bonds and storing it in the high energy bonds of ATP

26
Q

Glycolysis

A

Takes one 6 C molecule to another 6 C molecules and it splits into two 3 C molecules
-the 3 C molecules are then converted to other 3-C molecules until they are eventually converted to two pyruvate muscles
-2 ATP used and 4 produced (net yield of 2)

27
Q

Pyruvate to acetyl CoA

A

Aerobic
enters mitochondria
3-C pyruvate becomes 2-Carbin compound
becomes CO2
released into bloodstream and breathed out

28
Q

Pyruvate to lactate

A

Anaerobic
accepts H from glycolysis
pyruvate becomes lactate
coenzymes freed and return to glycolysis
cori cycle

29
Q

Glycerol and Fatty acids

A

Triglycerides are broken down into glycerol and fatty acids
-glycerol enters the pathway that converts glucose then makes acetyl CoA
-fatty acids are broken down via fatty acid oxidation, this forms abundant acetyl CoA, fatty acids cannot make glucose

30
Q

Amino Acids

A

Amino acids are deaminated before entering energy pathways
-several entry points for amino acids
- because they are converted to pyruvate they can be turned into glucose
-if they enter the TCA cycle directly they can also be made into glucose

31
Q

Glucogenic amino acids

A

Amino acids can be converted into glucose

32
Q

Ketogenic

A

Amino acids that are converted to acetyl CoA and can’t be made into glucose

33
Q

Electron transport chain

A

a series of proteins that accept electrons and pass them to the next carrier on the inner mitochondrial membrane
-as the coenzymes deliver theur electrons from the TCA cycle, glycolysis and fatty acid oxidation to the ETC, each carrier receives the electrons and passes them on to the next carrier.
-o2 accepts the electrons and combines with hydrogen atoms to produce water
-As the electrons are passed from carrier to carrier, H atoms are pumped across the membrane to the outer portion which are then later pumbed back into the inner portion (powers ATP synthesis)
- once formed ATP can travel into the cytosol where it can be used to drive cell function