chapter 7 - homeostasis of body temp / fluids Flashcards

1
Q

what are sources of heat input and output

A
  • input: heat from body processes (metabolism, respiration of liver and muscle cells), heat gained from surroundings by conduction and radiation
  • output: evaporation of water from skin and lungs, warm urine / faeces
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2
Q

explain cellular respiration

A
  • cellular respiration: food is oxidised in cells and energy is stored in chemical bonds in proteins, carbohydrates and fats and later released
  • energy is used for muscle contraction, active transport, anabolism, form of heat
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3
Q

explain metabolic rate

A
  • rate at which energy is released by the breakdown of food
  • body temp is usually higher than environmental due to metabolic activity (during exercise, MR increases, body temp therefore increases thus body needs to decrease temp; homeostasis)
  • factors affecting: exercise (more muscle activity increased MR x40, increased heat), stress (sympathetic division of ANS, more adrenaline / noradrenaline, increased MR, increased heat) and rising body temp by 1*C intervals causes increased MR x10
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4
Q

what is thermo regulation and why does it happen

A
  • maintaining the balance between heat production and heat loss
  • body temp must be around 36.8 which is optimum for cellular reactions and enzyme activity
  • increased temp can cause nerve malfunction, change in structure of proteins, denature of enzymes (deactivation if decreased temp), and death
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5
Q

how is the skin involved in temperature regulation

A
  • BV: carry blood to skin from core of body (lose heat through conduction, convection, radiation and evaporation)
  • BV diameter: controlled by ANS to increase / decrease BF to surface
  • sweating: when BV are dilated, active secretion of fluid by sweat glands / periodic contraction of cells surrounding ducts (sympathetic nerves stimulate production / transport of sweat to skin
  • > evaporation: of sweat = cooling effect when sweat (l) turns to vapour (g)
  • > absence: of sweat, continual loss of water via evaporation (lungs, respiratory system)
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6
Q

explain the types of heat transfer

A
  • conduction: heat is transferred to another object by direct contact (heat goes from hot object to cool object)
  • convection: when cool air makes contact with body it becomes warm (heat leaves body and vice versa), air moves away via convection currents (faster flow = faster transfer)
  • evaporation: conversion of (l) to (g), surface is subsequently cooled (via latent heat energy)
  • radiation: transfer of heat from one object to another without direct contact, heat leaves body in form of infrared radiation (heat radiates from body to cooler objects and vice versa)
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7
Q

how does the body prevent temp from falling

A
  • vasoconstriction: peripheral TR - hyp. - sympathetic NS - BV in skin - vasoconstriction - decreased BF of warm blood to skin - decrease heat loss
  • adrenaline / noradrenaline: central TR - hyp. - sympathetic NS - adrenal medulla - adrenaline / noradrenaline - increase MR - increase heat prod.
  • increase in MR: central TR - hyp. - RF - anterior pituitary - TSH - thyroid gland - thyroxine - increased MR - increased heat prod.
  • shivering: central TR - hyp. - cerebral cortex - increase skeletal muscle tone - oscillating / rhythmic muscle tremors - shivering - metabolic activity produces more heat
  • behavioural: central TR - hyp. - cerebral cortex - put on clothing / shelter from cold wind / eat to increase MR / heater / decrease SA - decreased heat loss
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8
Q

how does the body prevent temp from rising

A
  • vasodilation: peripheral TR - hyp. - sympathetic NS - BV in skin - vasodilation - skin is reddish / surface temp rises - increase heat loss (radiation / convection)
  • sweating: peripheral TR - hyp. - sympathetic NS - production / transfer of sweat to skin - periodic contraction of cells surrounding ducts / glands - increased heat loss (evaporation: only when not humid, environmental temp must be <37)
  • decreased MR: central TR - hyp - IF - anterior pituitary - decreases TSH to thyroid - decreased MR - decrease heat prod.
  • behavioural: central TR - hyp. - cerebral cortex - turn on fan / AC / remove clothing, decrease physical activity - increase heat loss / decrease heat prod.
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9
Q

explain heat stroke, heat exhaustion and hypothermia

A
  • HS: temp / relative humidity are high - difficult / little heat loss via - evaporation / radiation - increased body temp (regulating mechanisms cease) - >42 very serious / 44-46 is fatal - treatment (immerse in cold water)
  • HE: extreme sweating / vasodilation (body temp almost normal) - decrease V(plasma) / decrease resistance to BF - decreased BP - output from heart decreases
  • hypo: very low MR - heat production cannot restore - body temp continues to fall - death <32
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10
Q

describe the contents of intra and extra cellular fluid in the body

A
  • I: fluid inside cell (cytosol) 2/3 of total body water
  • E: plasma (1/4 of E fluid, fluid part of blood) and intercellular fluid (3/4 of E fluid, interstitial tissue / fluid, comprised of lymph, CSF, synovial fluid of eyes / ear / chest / abdominal cavities, around heart, alimentary canal and kidney filtrate)
  • the different fluids aren’t isolated, continual exchange of materials, water moves easily through plasma membranes
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11
Q

describe how fluid balance is maintained

A
  • fluid gain must equal fluid loss if composition is to be kept constant
  • water intake (2500mL): drink (1600), metabolic water (water produced from cellular respiration 200), food (700)
  • water loss (2500mL): faeces (200), kidneys (1500), skin (500), lungs (300)
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12
Q

describe the process of excretion

A
  • E: removal of waste products (from metabolism), from the body
  • lungs: excretion of CO2 and H2O (g), CO2 is produced during cellular respiration and cannot be used by the body
  • sweat glands: secrete water containing the by-products of metabolism (salt, urea, lactic acid)
  • alimentary canal: excretes bile products (breakdown products of haemoglobin), leaves body with faeces (with undigested food = not a by product = not made by cells)
  • kidneys: maintain constant conc. of materials in body fluids
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13
Q

go into detail about the kidneys

A
  • F: excrete water as urine (60% of water lost each day is via kidney)
  • regulation: water loss from lungs, alimentary canal and skin cannot be regulated, kidney can
  • S: kidneys (produce urine), nephron (functional unit, filtration / excretion), renal artery (B to K), renal vein (K to B), uretar (tube that leaves kidney with urine), bladder, urethra
  • nephron: 99% of water filtered through glomeruli is reabsorbed, occurs in PCT, loop of henle via osmosis and in DCT and CT via active transport (controlled by ADH)
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14
Q

how is water loss and salt loss controlled

A
  • low [H2O] and high osmotic pressure - osmoreceptors in hyp. - hyp. - ADH - posterior lobe - ADH - kidney - increased permeability to water of DCT and CT - increased reabsorption of water into peri tubular capillaries - increased [H2O] in plasma / decreased osmotic pressure
  • low osmotic pressure - osmoreceptors in hyp. - hyp. - RF - anterior lobe - ACTH - adrenal glands - aldosterone - increased permeability to salts (and water) of DCT and CT into peri tubular capillaries - increased [salt and water] in blood - increased osmotic pressure and BP (more volume)
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15
Q

how is water intake controlled

A
  • dehydration: water loss - intercellular fluid moves into plasma by osmosis - intercellular is more concentrated - water diffuses out of intracellular fluid - cells shrink
  • low water / reduction in plasma volume / increase in osmotic pressure / concentration of extracellular fluid - osmoreceptors in thirst centre in hyp. / stimuli of dry mouth - stimulation makes person feel thirsty - conscious response to drink - fluid consumed is absorbed into plasma by alimentary canal - enables inter / intra cellular fluid to return to proper osmotic conc. - excess fluid in extraC. is collected by lymph - returned to blood
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16
Q

what is dehydration and water intoxication

A
  • D: water loss exceed water intake, symptoms are noticeable after 2% loss of normal body water (severe thirst, low BP, dizziness / headache)
  • WI: body fluids become diluted (excessive sweating / loss of salts) and cells take in extra water via osmosis, lightheadedness, headache, vomiting, collapse