chapter 7: cell cycle + cell division Flashcards

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0
Q

alternation of generations

A

most plants
meioisis->haploid spores->mitosis->gametophyte->mitosis->gametes->gametes fuse to create zygote->mitosis->diploid sporophyte
back to meiosis

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1
Q

haplontic organisms

A

zygote is the only diploid cell.
once formed, meiosis->haploid cells, usually spores
spores are germinated to form new haploid organism

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2
Q

diplontic organisms

A

gametes are the only haploid cells

mature organism is diploid

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3
Q

sexual reproduction

A

random selection of half of the diploid chromosome set to make a haploid gamete
then diffusion of haploid gametes from separate parents to form diploid cell

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4
Q

segregation

A
  • part of cell division where replicated dna is distributed to the two new cells
  • ori regions move to opposite ends of cell
  • active process
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5
Q

cell division

A
  1. reproductive signal
  2. replication of dna
  3. segregation of dna
  4. cytokinesis
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6
Q

binary fission

A

cell division in prokaryotes

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7
Q

prokaryotic chromosome

A

ori: origin of replication site
ter: termination site of replication

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8
Q

mitosis, then cutokinesis

A
  • cell division in eukaryotic cells
  • requirements:
    1. replication of dna
    2. segregation of dna, then mitosis
    3. cytokinesis
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9
Q

interphase

A

g1 (g0). s, g2 phases

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10
Q

prophase

A
  • first stage of mitosis
  • condensed chromosomes
  • centrosome (determines spatial relationship of two new cells)
  • spindle
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11
Q

kinetochores

A
  • specialized proteins on the centromeres of sister chromatids that help with movement
  • are involved withe condensed chromosomes during prophase
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12
Q

karyotype

A

number and size of condensed chromosomes

can identify organisms by it

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13
Q

prometaphase

A

nuclear envelop breaks down

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14
Q

metaphase

A

chromosomes line up at midline of cell, equatorial position

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15
Q

anaphase

A

chromatids separate and daughter chromosomes move away from each other toward poles

16
Q

polar microtubules

A
  • form framework of spindle

- from pole to pole, keepinf them apart

17
Q

kinetechore microtubules

A
  • become attached to sister chromatids from opposite sides of cell
  • acts as molecular motor, pulling them away from each other toward poles
18
Q

telophase

A

nuclear envelope forms around each new set of chromosomes

—>two new nuclei in cell

19
Q

contractile ring

A

furrow of cytokinesis in animal cells, pinching the cell in two

20
Q

cell plate

A

beginning of new cell wall during cytokinesis of plants

21
Q

growth factors

A

signal to stimulate cell division/differentiation in eukaryotic cells

22
Q

cyclin-dependent kinase

A

-enzyme that regulates cell cycle

growth factor->cyclin synthesis->cdk activation-> cell cycle events

23
Q

functions of meiosis

A
  • reduce chromosome number from diploid to haploid
  • ensures haploid products have complete set of chromosomes
  • genetic diversity
24
Q

meiosis 1

A
  • homologous chromosomes come together and line up
  • homologous chromosome pairs separate, but the individual chromosomes (each consisting of 2 sister chromatids) remain intact
25
Q

meoisis 2

A

separates sister chromatids

result: 4 genetically different cells

26
Q

crossing over

A
  • chiasma=points at which homologous chromosomes are attached
  • genetic marerial is exchanged
  • results in recombinant chromatids (genetic variation)
27
Q

independent assortment

A
  • different possibilities of lineup at metaphase 1

- total chance for which homologous pair goes to which daughter cell

28
Q

nondisjunction

A

-meiotic error where homologous chromosome pair fails to separate in anaphase 1 or chromatids dont separate in anaphase 2

29
Q

aneuploidy

A

when nondisjuntion causes trisomy (having extra chromosome) or monosomy (missinf chromosome)

30
Q

polyploidy

A
  • meiotic error when triploid, tetraploid, or higher order polyploid nuclei form
  • can occur if there is an extra round of dna replication or no spindle formation
  • occurs naturally in some animals, leads to speciation
31
Q

translocation

A
  • meiotic error when chromatids from homologous chromosomes pairs break and rejoin
  • changes location of genes relative to other dna sequences
32
Q

necrosis

A
  • when cells are damaged by mechanical means or starved of nutrients
  • cells swell and burst
33
Q

apoptosis

A
  • genetically programmed series of events that cause cell death, aka cell suicide
  • cell detaches from neighbors, hydrolizes dna into small fragments, and breaks these fragments up
  • reasons:
    1. cell is no longer needed
    2. the older the cell, the more prone it is to genetic damage that could lead to cancer
34
Q

hypersensitive response

A

when plants use apoptosis to protect themselves from disease

35
Q

caspases

A

enzymes that are important to apoptosis because they hydrolyze the target molecules

36
Q

oncogene

A
  • positive regulators of cell cycle in cancer cells

- stimulate cancer cells to divide more often

37
Q

tumor suppressors

A
  • negative regulators of cell cycle in normal cells, but are inactive in cancer cells
  • tells cell cycle to not proceed