CHAPTER 7: CARTILAGE Flashcards

1
Q

a tough, durable form of supporting connective
tissue

A

Cartilage

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2
Q

characterized by an extracellular matrix (ECM) with
high concentrations of GAGs and proteoglycans,
interacting with collagen and elastic fibers.

A

Cartilage

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3
Q

consists of cells called chondrocytes embedded in
the ECM

A

Cartilage

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4
Q

physical properties depends on electrostatic bonds
between type II collagen fibrils, hyaluronan, and the
sulfated GAGs on densely packed proteoglycans

A

Cartilage

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5
Q

lack vascular supplies and chondrocytes receive
nutrients by diffusion from capillaries in surrounding
connective tissue

A

Cartilage

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6
Q

o Lacks nerves

A

Cartilage

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7
Q

3 TYPES OF CARTILAGE

A

Hyaline, Elastic, fibrocartilage

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8
Q

Synthesize and maintain all ECM components

A

Chondrocytes

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9
Q

located in matrix cavities

A

Chondrocytes

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10
Q

exhibit low metabolic activit

A

Lacunae

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11
Q

Young chondrocytes are called _________ which
have an elliptic shape, with the long axes parallel to
the surface

A

chondroblast

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12
Q
  • chondrocyte found deeper
    in cartilage and appear in groups
A

Isogenous Aggregates-

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13
Q

a sheath of dense connective tissue that surrounds
cartilage in most place

A

Perichondrium

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14
Q

forms an interface between the cartilage and the
tissues supported by the cartilage.

A
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15
Q

harbors the blood supply serving the cartilage

A
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16
Q

covers all hyaline cartilage except in articular
cartilage of joints

A
17
Q

essential for the growth and maintenance of
cartilage

A
18
Q

The outer region of the perichondrium consists
largely of _______ and fibroblasts
o inner layer adjoining the cartilage matrix also
contains ____________

A

collagen type I fibers

mesenchymal stem cells

19
Q

avascular,
o Where the dry weight of hyaline cartilage is
embedded

A
20
Q

generally basophilic and the thin collagen fibrils are
barely discernible.
o Composed of chondronectin a structural
multiadhesive glycoprotein which binds specifically
to GAGs, collagen, and integrins, mediating the
adherence of chondrocytes to the ECM.

A

Matrix