Chapter 7 Flashcards

1
Q

Alpha Particle are very ______

A

Heavy

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2
Q

Alpha Particles causes superficial ________

A

Skin Damage

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3
Q

Alpha particles can be stopped by ________________\

A

Black construction paper

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4
Q

Instability of an atom caused by addition or removal of electrons.

A

Ionization

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5
Q

Amount of energy deposited in tissue over path of radiation beam.

A

Linear energy transfer (LET)

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6
Q

Low ____ radiation deposits little energy in tissue such as x-rays and gamma rays.

A

LET

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7
Q

High ____ radiation deposits greater energy in tissue like alpha.

A

LET

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8
Q

High____ is potentially dangerous if implanted (prostate seeds) or ingested, injected, or inhaled in nuclear medicine.

A

LET

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9
Q

Relative damage to tissues due to radiation being deposited.

A

Relative Biological Effectiveness (RBE)

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10
Q

LET & RBE are __________ proportional.

A

Directly

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11
Q

Radiation absorbed dose used to measure amount of radiation deposited in any object living or inanimate.
Traditional Unit ____
Systems International Unit _____

A

Trad- Rad

SI- Gray

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12
Q

Radiation equivalent to man used to measure radiation absorbed in human tissue only.
Traditional Unit-
SI -

A

Trad- Rem

SI - seirvert

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13
Q

Measure ionization in air or in air exposure
Trad-
SI-

A

Trad- roentgen

SI- coulombs

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14
Q

Used to measure radioactivity (usually Nuclear Medicine)
Trad-
SI-

A

Trad- curie

SI - Becquerel

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15
Q

Rads x QF =

A

REMS

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16
Q

Grays x QF =

A

Seiverts

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17
Q

X-Ray, Beta Particle, Gamma Rays have a quality factor of?

18
Q

Alpha Particles, Fast Neutrons has a quality factor of?

19
Q

QF is similar to Radiation or ____________

A

Tissue Weighting Factor

20
Q

Tissue irradiated under oxygenated or aerobic conditions is more sensitive to radiation than when irradiated under anoxic or hypoxia conditions

A

Oxygen Enhancement Ration OER

21
Q

Alpha particles consist of ____ Protons and ______ Neutrons

A

2 Protons 2 Neutrons

22
Q

What is important in Radiation Therapy because healthy, oxygenated tissue may not require as much radiation to kill cancer cells.

23
Q

Young cells more vulnerable to radiation damage. Examples- Stem, immature, precursor, undifferentiated cells.

A

Law of Bergonie and Tribondeau

24
Q

____ action of damage to cells from radiation occurs 5% of the time (direct hit to DNA)

25
____ action of damage to ells from radiation occurs 95% of the time (due to radiolysis of water)
Indirect
26
Radiolysis of water can result in formation of?
Free Radicals
27
Extremely unstable, can travel and cause point lesions away from area that was irradiated.
Free Radicals
28
Hydroxyl Radical (OH*) and Hydroperoxyl Radical (HO2*)
Types of Free Radicals formed
29
Two Hydroxyl Radicals (OH*) can combine to form Hydrogen Peroxide (H2O2) which is ________
Toxic to the cell
30
When radiation interacts with DNA and serves a side rail or rung of the DNA ladder. Repair enzymes are capable of reversing some point mutations.
Point Mutation
31
photomicrograph of chromosome that shows damage from radiation
Karotype
32
___ is the mastermind of the cell and necessary for cell survival.
DNA
33
A whole body dose of __GY ____Rads depresses blood cell count Threshold Dose
.25gy 25 Rads
34
Lethal Dose or 3-4gy (300-400 Rads) that may kill 50% or exposed population in 60 Days
LD 50/60
35
______ are the most radiosensitive cells in the body.
Lymphocyte
36
______ are the least radiosensitive cells in the body.
Adult nerve cells
37
_____ are the least radioresistant in the body.
Lymphocyte
38
_____ are the most radioresistant in the body.
Adult nerve cells
39
__ gy ___ rads may cause temporary sterility in makes and females (Threshold dress)
2gy 200 Rads
40
__gy and __rads may cause permanent sterility in females
5gy 500 Rads
41
__gy and __ rads may cause permanent sterility in males
5-6 gy 500-600 Rads