chapter 6.1-6.2

Question 1

recessive alleles usually result from

Answer 1

a mutation that inactivates the affected gene, causing loss of function

Question 2

dominant alleles are often the consequence of

Answer 2

a mutation that causes some kind of gain of function, for example, increasing activity of the encoded protein, conferring a new function to it, or affecting its temporal or spatial pattern of expression

Question 3

what are the types of point mutations

Answer 3

silent, missense, nonsense, frameshift

Question 4

in the first generation when analyzing a dominant mutation…

Answer 4

all offspring have the mutation

Question 5

in the second generation when analyzing a dominant mutation…

Answer 5

3/4 offspring have the mutant phenotype

Question 6

in the first generation when analyzing a recessive mutation…

Answer 6

no offspring have the mutant phenotype

Question 7

in the second generation when analyzing a recessive mutation…

Answer 7

1/4 offspring have the mutant phenotype

Question 8

complementation analysis determines

Answer 8

whether recessive mutations are in the same or different genes

Question 9

in yeast complementation analysis, what does growth indicate

Answer 9

mutations are in different genes

Question 10

in yeast complementation analysis, no growth indicates

Answer 10

that mutations are in the same genes because both alleles are nonfunctional