Chapter 6 - Serotonin Flashcards
1
Q
Where is Serotonin synthesized from?
A
Tryptophan. Must get from diet
2
Q
What are the 2 enzymatic steps to get to Serotonin?
A
Tryptophan hydroxylase >>>>>>>>> Aromatic Amino Acid Decarboxylase >>>>>>>>> Serotonin
3
Q
How is 5-HT blocked?
A
By:
- SSRIs (prozac)
- Cocaine / MDMA
4
Q
When is 5-HT activity highest?
A
During waking arousal
5
Q
When is 5-HT reduced and absent?
A
Reduced in quiet waking? and SWS
Absent in REM sleep
6
Q
What are the 2 types of axon terminals?
A
- ) Fine axons with small varicosities
2. ) Beaded axons with large spherical varicosities
