Chapter 6

Question 1

At about what periods in history did cocaine reach its first and second peaks of popularity, and when was amphetamine’s popularity at its highest?

Answer 1

cocaine- late 19th century
amphetamine- 1960’s

Question 2

How did Mariani, Halsted, and Freud popularized the use of cocaine?

Answer 2

Mariani put it in wine, Halstead used it for local anesthesia and Freud used it for depression and morphine addiction

Question 3

How are coca paste, freebase, and crack similar?

Answer 3

they are made from the coca plant and are all forms of cocaine

Question 4

Following cocaine use, how long does it take for the drug (or it’s metabolites) to be eliminated from the body and not detected in the urine?

Answer 4

about 3 days after your last dose

Question 5

What similarities and what differences are there in the toxic effects of cocaine and amphetamine?

Answer 5

similarities- extended use leads to paranoia
differences- they are not compatible (if combined they can make a bomb)

Question 6

How would medical practice be affected if both cocaine and amphetamine were placed on Schedule I?

Answer 6

cocaine- couldn’t be used as a local anesthetic
amphetamine- couldn’t be used for ADHD

Question 7

How does the chemical difference between methamphetamine and amphetamine relate to the behavioral effects of the two drugs?

Answer 7

amphetamines- are still used today as an adjunctive therapy to treat depression
methamphetamine- is more potent so it takes less to get a greater effect

Question 8

Compare the dependence potential of cocaine with that of amphetamine.

Answer 8

you can be addicted to both if you use it enough. They are rarely used because they have a high potential of addiction. They have a high potency of addiction and must be measured carefully.

Question 9

Describe the effects of amphetamines on mental performance.

Answer 9

reduce activity levels and improve concentration in hyperactive children and adults