Chapter 6 Flashcards
What are active sites
Unique micro environments that bind substrates and catalyze reaction
What does initial binding to active site depend on
Weak non covalent interactions (IMF)
LD
Salt bridge
HB
What is an absolute enzyme
Only one substrate binds
What is relative enzyme
Biden few similar substrates
What is steriospecific enzyme
Only bind one type sterioisomer
What are the 2 types of geometric complementary
Lock and key
Induced fit
What is electronic complementary
Substrate and enzyme have opposite charges
What are the 2 types of coenzymes and what are main differences
Prosthetic (tightly bound recycled in place) and cosubstrate (weakly bound, recycled elsewhere)
What are enzyme active sites
Specific micro environment, depends of 3D Structure
What are the 2 types of cofactors
Inorganic metal
Organic coenzyme
Why do we need vitamins
Vitamins are converted to necessary coenzymes
What is binding energy
Binding energy is free energy released when 2 or more molecules bind together such as enzyme and substrate
What is apoenzyme
Enzyme minus cofactor
What is holoenzyme
Enzyme plus cofactor
What are coenzymes
Small vitamin derived organic cofactors
