Chapter 16 + 17 Flashcards

1
Q

Hexokinase

A

Phosphorylates glucose

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2
Q

Phosphoglucose isomer add

A

Converts glucose 6 phosphate into fructose 6 phosphate

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3
Q

Phosphofructokinase

A

Forms fructose 1 6 bisphosphate

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4
Q

Aldolase

A

Cleaves fructose 1 6 bisphosphate

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5
Q

Triode phosphate isomerase

A

Catalyze the inter conversion of 3 carbon isomers

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6
Q

Goyceraldehyde 3 phosphate dehydrogenase

A

Generates the first high phosphoryl transfer that is not ATP

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7
Q

Phosphoglycerate

A

Generates first molecule ATP

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8
Q

Phosphoglycerate mutate

A

Converts 3 phosphoglycerate into 2 phosphoglycerate

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9
Q

Enolase

A

Generate second high phosphoryl transfer potential not ATP

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10
Q

Pyruvate kinase

A

Generates second molecule ATP

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11
Q

In fermentation what is donor and acceptor

A

Glyceraldehyde 3 phosphate is donor

Pyruvate in lactic and acetylaldehyde in alcohol are acceptors

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12
Q

Why is glucokimase important

A

When max ATP hexokinase inhibited and want to still make and store

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13
Q

Why do we need niacin

A

Make NAD+

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14
Q

Why can’t we reverse glycolysis

A

Some reactions are far to exergonic

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15
Q

What is fate of puruvate

A

Ethanol lactic acid

H20 CO2

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16
Q

What is effect of lactic acid buildup

A

Lower pH highly acidic

17
Q

What does fructose 2 6 bisphosphate do in terms of allosteric

A

Stabilizes R state

18
Q

Why can’t we just run glycolysis in reverse

A

Highly endergonic steps

19
Q

What generates pyruvate

A

Protein
Lactate
Glycerol

20
Q

Pyruvate carboxylase

A

Generates oxaloacetate

21
Q

Acetyl coA

A

Required for pyruvate carboxylase activity

22
Q

Phosphoenolpyruvate carboxykinase

A

Generate high phosphoryl transfer potential compound

23
Q

Glycerol

A

Readily converted to DHAP

24
Q

Fructose 1 6 bisphosphotase

A

Gluconeogenic counterpart of PFK

25
Q

Glucose 6 phosphatase

A

Found predominantly in liver

26
Q

Why does gluconeogenesis occur during exercise

A

Lactic acid is produced and need to get rid of it as highly acidic so liver removes and turns to pyruvate and makes glucose to use or store as glycogen

27
Q

How many high energy molecules are required to synthesize one molecule of glucose for 2 molecules pyruvate

A

4 ATP 2 GTP 2 NADH

28
Q

Glycolysis goes when

A

High AMP
High fructose 2 6 bisphosphate
Increase insulin
Fed

29
Q

Gluconeogenesis goes when

A
High ATP
Increase citrate 
Increase acetyl coA
Increase glucagon
Fasting