Chapter 55 - Psychotic Disorders

Question 1

chlorpromazine (Thorazine)

Answer 1

Class: Phenothiazine Antipsychotics (“typical”)

Question 2

chlorpromazine (Thorazine)
MOA:
Uses:
AE:

Answer 2

MOA: Blocks the postsynaptic dopamine receptors in the brain
Uses: Schizophrenia, psychosis
AE: Extrapyramidal effects, CNS effects, cardiovascular effects, hematologic effects

Question 3

haloperidol (Haldol)

Answer 3

Class: Nonphenothiazines (“typical”)

Question 4

haloperidol (Haldol)
MOA:
Uses:
AE:
BBW:

Answer 4

MOA: Produces antipsychotic effects by blocking the postsynaptic dopamine receptors in the brain.
Uses: Schizophrenia, psychotic disorders
AE: Cardiovascular effects, CNS effects, extrapyramidal symptoms, dermatologic effects, GU effects, metabolic and respiratory effects
BBW: withdrawl symptoms in newborns, risk of death in older adults with dementia

Question 5

clozapine (Clozaril)

Answer 5

Class: Atypical Antipsychotics

Question 6

clozapine (Clozaril) 
MOA: 
Uses: 
AE:
BBW:

Answer 6

MOA: Blocks the dopamine receptors in the brain, depressing the RAS, also blocks serotonin and glutamate receptors
Uses: Schizophrenia, psychosis (recurrent SI), schizoaffective disorder
AE: Cardiovascular/CNS/hematologic/metabolic effects
BBW: Increases seizure risk, fatal agranulocytosis, hyperglycemia

Question 7

• aripiprazole (Abilify)
• olanzapine (Zyprexa)
• quetiapine (Seroquel)
• risperidone (Risperdal)
• ziprasidone (Geodone)

Answer 7

Class: Atypical Antipsychotics