Chapter 5.3 Flashcards
Hemophilia
referred to as the “royal disease” due to its spread to the royal families of Europe through Queen Victoria’s descendants
What is hemophilia?
the inability to form blood clots to prevent bleeding out
Chromosome theory of inheritance
- genes are located at specific positions on chromosomes
- segregation and assortment of these chromosomes during meiosis is responsible for inheritance patterns
Gene locus (gene loci)
site on a chromosome that a specific gene occupies
Who does hemophilia affect?
Mostly males, 1 in 10,000
Where do alleles of a gene reside on homologous chromosomes?
at the same locus
What makes an organism heterozygous/homozygous
homologous chromosomes having same/different alleles at a particular locus
Genetic linkage
tendency for alleles for different genes on the same chromosome to be inherited together
Linked genes
genes with loci that are close together
Recombination frequency
frequency with which certain genes turn up together
What is recombination frequency used for?
to map distance between gene loci on a chromosome
Gene map
diagram that shows relative locations and distances of genes on a chromosome
Where is the gene involved in white eye inheritance found?
on the x chromosome
If genes are located on separate chromosomes…
they assort independently during meiosis
If genes are located on the same chromosomes…
less likely to assort independently