Chapter 50 Flashcards
1
Q
What are the two types of PNS disorders?
A
Neuromuscular
Cranial nerve disorders
2
Q
What does the PNS involve?
A
The nerves of arms, legs, chest, abdomen
3
Q
What are the 4 neuromuscular disorders we are talking about?
A
MS
Myasthenia Gravis
ALS
Gullian-Barre Syndrome
4
Q
What do the neuromuscular disorders do?
A
They disrupt the transmission of impulses between neurons and the muscles they stimulate
5
Q
What is the myelin sheath?
A
It covers the axons and is responsible for the smooth transmission of nerve impulses
6
Q
What is MS?
A
involves the degeneration of myelin sheath
7
Q
How can the myelin sheath be damaged?
A
It can be damaged due to inflammation, detachment or if it becomes swollen
8
Q
How can myelin repair itself?
A
exacerbation followed by remission
9
Q
What is the etiology of MS?
A
Unknown, could be possible autoimmune response, possible viral infection, or heredity
10
Q
What are the two types of MS?
A
Relapsing remitting and progressive
11
Q
What is relapsing remitting MS?
A
Worsening signs and symptoms followed with improvement
12
Q
What is progressive MS?
A
gets worse without improvement
13
Q
What is the most common type of MS?
A
relapsing remitting
14
Q
What are some problems associated with MS? (S/S)
A
Weakness/paralysis of limbs Double/blurred vision Slurred speech Spasticity of muscles Numbness Tinnitus and vertigo Dysphagia Spastic or flaccid bladder Mood swings
15
Q
What do the symptoms depend on for MS?
A
The symptoms depend on the area with the sclerosed myelin
16
Q
What are some different factors that can trigger the onset of symptoms of MS?
A
Extreme heat, extreme cold, fatigue, infection and emotional stress
17
Q
How does death usually occur in MS?
A
death usually results from infection
18
Q
Therapeutic interventions for MS?
A
Steroids Immunosuppressants Anticonvulsants Muscle relaxants PT/OT
19
Q
What is acetylcholine needed for?
A
Muscle contraction
20
Q
What happens during myasthenia gravis?
A
If there is no acetylcholine or the receptors for acetylcholine are destroyed, the muscle contraction doesn’t take place
21
Q
The muscle weakness in myasthenia gravis occurs during activity and improves with ____
A
rest
22
Q
Myasthenia gravis affects ?
A
facial muscles, neck and limb movement
23
Q
S/S of myasthenia gravis?
A
Progressive muscle weakness Fatigue with activity Ptosis Difficulty chewing and swallowing Difficulty breathing An early sign can be double vision or slurred speech
24
Q
What is a myasthenic crisis?
A
Sudden onset of symptoms due to not enough medication or triggered by infection
25
What are two complications of myasthenia gravis?
Aspiration
| Respiratory infection and failure
26
How does a cholinergic crisis occur?
Due to overmedication
27
What two meds are given for myasthenia gravis?
Anticholinesterase drugs
| Corticosteroids
28
Why are corticosteroids given for myasthenia gravis?
Inhibit the immune system and the production of abnormal antibodies
29
Why are anticholinesterase drugs given for myasthenia gravis?
Help improve nerve-muscle communications and increase the muscle strength
30
What is a tension test that is used to diagnosed myasthenia gravis?
Anicholinergic med is given and there is a temporary improvement of droopy eyelids (ptosis). It is an injection of tensilon and muscle strength improves for 1-3 mins
31
Why would you remove the thymus as a therapeutic intervention for myasthenia gravis?
This will work on the immune system so it doesn't work against the body
32
How are meds used as a therapeutic intervention for myasthenia gravis?
They improve neuromuscular transmission and increase muscle strength. They also slow down the time of acetylcholine breakdown
33
What is ALS (amyotrophic lateral sclerosis)
Motor neurons degenerate (they stop sending messages and nerve impulse transmission is then blocked)
This results in muscle weakness and atrophy
34
As ALS progresses, it effects the muscles that control ____ and ____
breathing, swallowing
35
What is the etiology for ALS?
Unknown, but it may be due to possible genetic disposition or possible auto-immune disorder
36
ALS does NOT effect the brain, only ?
motor neurons
37
ALS causes what?
both the upper and lower motor neurons that control voluntary movement to die off.
This then leads to weakness, muscle death and then paralysis
38
What is pulmonary compromise in ALS?
This is when the muscles of the diaphragm are effected. They eventually end up on a ventilator
39
When does death usually occur after diagnosis of ALS?
3-5 years
40
How can ALS be diagnosed?
assessment of symptoms and a nerve biopsy
41
S/S of ALS?
```
Progressive muscle weakness (gradual): The muscles weaken and waste away
Decreased coordination
Muscle spasms
Difficulty chewing and swallowing
Speech difficulty
```
42
Therapeutic interventions for ALS?
Muscle relaxants (to control muscle spasticity and cramps)
PT/OT/Speech therapy
Pain control
Infection precautions
Good skin care
Communication support
-All aimed at improving function as long as possible
43
Is there a cure for ALS?
no
44
What is Guillain-Barre syndrome?
Myelin sheath of the spinal cord and cranial nerves is destroyed due to an inflammatory reaction which cause a slowed or blocked nerve conduction
45
What are the two main categories of Guillain-Barre syndrome?
Ascending and descending
46
What is ascending Guillain-Barre syndrome?
Characterized by progressive weakness beginning in the legs and works it's way up the body
47
What is descending Guillain-Barre syndrome?
Affects the cranial nerves of the brain stem first, making difficulty in swallowing and speaking and progresses downward to the legs (less common)
48
What are complications of Guillain-Barre syndrome?
Respiratory failure
Infection
Depression
49
Therapeutic interventions for Guillain-Barre syndrome?
```
The goal of therapy is to support body systems until the patient recovers
Monitor respiratory status
Manage pain
Tube feedings if indicated
Communication board
```
50
What is another name for trigeminal neuralgia?
Tic douloureux
51
What is the pathophysiology of trigeminal neuralgia?
Involved the 5th cranial nerve (has 3 different branches so it effects different parts of the face)
Affected are the forehead, nose, cheek and jaw
52
What might cause trigeminal neuralgia?
May be from irritation or chronic compression of the cranial nerve
53
S/S of trigeminal neuralgia?
Intense pain on one side of the face
Periods of pain last from seconds to minutes and can last several days
Triggered by items touching the face or talking
Sleep provides a period of relief
As time progresses, the episodes become more frequent
54
Why are anticonvulsants used as a treatment for trigeminal neuralgia?
They reduce transmission of nerve impulses
55
Why are nerve blocks used as a treatment for trigeminal neuralgia?
Provides a longer period of relief than meds
56
Why is surgery used as a treatment for trigeminal neuralgia?
It is used to remove the nerve or to pad it
57
What is the pathophysiology of Bell's palsy?
Cranial nerve #7 is affected
| Patient loses motor control on one side of the face
58
What is the action of the 7th cranial nerve?
It controls most facial muscles, ears, and salivation/tearing
59
What is the etiology of Bell's palsy?
Unknown, but can be due to possible viral infection of nerve. Can also occur in 3rd trimester of pregnancy
60
S/S of Bell's Palsy?
One sided facial nerve quits working
- Speech difficulties
- Weakness (mouth droops and can't close eye)
61
__% of patients with Bell's palsy will have complete recovery in a short period of time
50
62
Why is prednisone used for Bell's palsy?
To decrease edema and swelling
63
Why is gentle massage used for Bell's palsy?
Keeps the face flexible for when it heals
64
Why is an eye patch and drops used for Bell's palsy?
Used to decrease the drying of the eyes
65
A patient with trigeminal neuralgia asks the nurse why carbamazepine (Tegretol) has been ordered. Which response is best?
a) "It will help decrease the inflammation in your nervous system"
b) "It will depress your immune system, which can slow the progression of the disease"
c) "It can help relieve nerve pain"
d) "It is an anticonvulsant to prevent seizures"
c) "It can help relieve nerve pain"
66
A patient with a myotrophic lateral sclerosis (ALS) expresses concern about not having enough breath to sing anymore. Which explanation by the nurse is best?
a) "ALS can damage the nerves to your bronchi and bronchioles, causing constriction and reduced airflow"
b) "The demyelination of your nerves caused by ALS causes confusion in the impulses to your lungs"
c) "ALS can affect your vocal cords, making it difficult to form sounds as you sing or speak"
d) "ALS may be affecting the nerves that go to your respiratory muscles, making them weak"
d) "ALS may be affecting the nerves that go to your respiratory muscles, making them weak"
67
A patient who is newly diagnosed with ALS says to the nurse, "I do not want to be kept alive on machines." Which nursing action is best in response
a) Ask the patient if he has advance directives and provide information about preparing them
b) Reassure the patient that he will not need to make decisions about machines for a long time
c) Inform the patient that individuals with ALS are not candidates for artificial ventilation
d) Explain to the patient that a ventilator will be necessary to keep him breathing as his disease progresses
a) Ask the patient if he has advance directives and provide information about preparing them
68
When caring for a patient admitted with Guillain-Barre syndrome, which nursing diagnosis should take priority?
a) Anxiety
b) Imbalanced Nutrition
c) Impaired Gas Exchange
d) Impaired Mobility
c) Impaired Gas Exchange
69
Which nursing interventions are appropriate for the patient with Bell's palsy? (Select all that apply)
a) Administer moisturizing eyedrops
b) Apply an eye patch
c) Avoid touching the patient's face
d) Apply warm compresses
e) Provide facial massage
f) Teach the patient to protect the face from cool breezes
a, b, d, e
70
Which meal would be the best choice for patient with myasthenia gravis?
a) Baked chicken sandwich, fresh carrots, apple
b) Meatloaf, mashed potatoes, canned green beans
c) Steak, baked potato, green salad
d) Tacos, fresh vegetables, sliced peaches
b) Meatloaf, mashed potatoes, canned green beans
71
How will the visiting nurse caring for a patient with myasthenia gravis and severe muscle weakness know if interventions have been effective?
a) The patient verbalizes satisfaction with the plan of care
b) The patient states understanding of the medication regimen
c) The patient and family state that no further home visits are needed
d) The patient is able to perform ADLs with SaO2 remaining at 95%
d) The patient is able to perform ADLs with SaO2 remaining at 95%
72
Muscles that are not used become wasted, or ___
atrophied
73
Some diseases are characterized by remissions and _____
exacerbations
74
Nerve pain is also called ____
neuralgia
75
An early symptom of myasthenia gravis is drooping eyelids, also called ____
ptosis
76
Symptoms of Guillain-Barre syndrome are caused by ______ of axons
demyelination
77
Myasthenia gravis is sometimes treated with _____, which separates blood cells from plasma to remove antibodies
plasmaphoresis
78
Muscle twitching, or ______, occur in amyotrophic lateral sclerosis
fasciculations
79
Medications for myasthenia gravis that can increase acetylcholine at the neuromuscular junction are called _______ agents
anticholinesterase
80
Which drug class is used to reduce muscle symptoms of muscle weakness from myasthenia gravis?
a) Anticholinesterase drugs
a) Anticholinergic drugs
c) Adrenergic drugs
d) Beta-blocker drugs
a) Anticholinesterase drugs
81
Which of the following nursing interventions will help prevent complications in the patient with Bell's palsy?
a) Megavitamin therapy
b) Elastic bandages
c) Application of ice to the affected are
d) Lubricating eyedrops
d) Lubricating eyedrops
82
Which data collection activity will help the nurse determine if the patient with Bell's palsy is receiving adequate nutrition?
a) Monitor meal trays
b) Measure intake and output
c) Check twice-weekly weights
d) Evaluate swallowing reflex
c) Check twice-weekly weights
83
A 32-year-old patient is admitted to a medical unit with a diagnosis of Guillain-Barre syndrome. The patient's legs are weak, causing difficulty walking without assistance. Which of the following is most likely responsible for this syndrome?
a) Bacterial infection
b) Heredity
c) High-fat diet
d) Autoimmune reaction
d) Autoimmune reaction
84
Patients with Guillain-Barre syndrome should be closely monitored. Which of the following lab results is most important to monitor for acute complications?
a) Blood urea nitrogen (BUN) and creatinine
b) Arterial blood gases (ABG)
c) Hemoglobin (HgB) and hematocrit (Hct)
d) Serum potassium
b) Arterial blood gases (ABG)
85
A woman sees her primary care provider because of extreme fatigue for the past 2 months; she has difficulty lifting even light objects. Her physician suspects myasthenia gravis. Which of the following tests should the nurse anticipate assisting with to confirm this diagnosis?
a) Mestinon test
b) Quinine tolerance test
c) Pulmonary function studies
d) Tensilon test
d) Tensilon test
86
A 39-year-old patient sees the physician after falling twice for seemingly no reason. Diagnostic tests are done, and the patient is diagnosed with multiple sclerosis. Which of the following explanations will help the patient understand the disease?
a) "You have a buildup of myelin in your nervous system, causing congestion and muscle weakness"
b) "You are missing a neurotransmitter that is important to muscle contraction"
c) "The receptor sites on your muscles are damaged, so they can't contract correctly"
d) "The insulation on your nerve cells is damaged, which slows the impulses to the muscles"
d) "The insulation on your nerve cells is damaged, which slows the impulses to the muscles"
87
A patient who is newly diagnosed with multiple sclerosis asks what medications are used to help control symptoms and treat the disease. Which of the following medications would the nurse include in the teaching?
a) Acyclovir (Zovirax)
b) Adrenocorticotropic hormone (ACTH)
c) Thyrotropin
d) Diphenhydramine (Benadryl)
b) Adrenocorticotropic hormone (ACTH)
88
A home care nurse is developing a plan of care designed to prevent complications in a patient with impaired respiratory function. Which of the following would the nurse include in the plan?
a) Antibiotics as needed
b) Elevate the head of the bed
c) Bedrest
d) Suction q4h
b) Elevate the head of the bed
89
The nurse notes frequent muscle twitching when collecting admission data on a patient admitted for increasing muscle weakness. Which of the following terms should be used to document this?
a) Fasciculations
b) Atrophy
c) Chorea
d) Neuropathy
a) Fasciculations
90
A 19-year-old student develops trigeminal neuralgia. Which of the following actions is most likely to trigger pain?
a) Sleeping
b) Eating
c) Reading
d) Cooking
b) Eating
91
What do cholinesterase inhibitors do and what are some examples?
Increase acetylcholine at synapses
- neostigmine (Prostigmin)
- pyridostigmine (mestinon)
- edrophonium chloride (Tensilon, used in diagnosis)
92
What do glucocorticoids do and what are some examples?
Reduce inflammation
- prednisone
- prednisolone
- prednisolone acetate or sodium phosphate
93
What do immunosuppressants do and what are some examples?
Suppress immunity and antibody formation
- azathioprine (Imuran)
- cyclophosphamide (Cytoxan)
94
What do antispasmodics/muscle relaxants do and what are some examples?
Relax muscles, reduce pain
- dantrolene (Dantrium)
- baclofen (Lioresal)
- diazepam (Valium)
- tizanidine (Zanaflex)
95
What do anticonvulsants do and what are some examples?
Treat nerve pain
- phenytoin (Dilantin)
- carbamazepine (Tegretol)
- gabapentin (Neurontin)
96
What does a glutamate antagonist do and what is an example?
Delays progression of ALS
| -riluzole (Rilutek)
97
Anticholinesterase drugs should be scheduled how?
They should be scheduled so that peak action occurs at times when increased muscle strength is need
98
What is another name for Guillain-Barre syndrome?
acute inflammatory polyneuropathy
