Chapter 5: The Integumentary System Flashcards
Epidermis
Superficial region
Dermis
Middle region
Hypodermis
Deepest region
The epidermis is made up of
Stratified squamous epithelium
Keratinocytes produce
Fibrous protein keratin
Melanocytes produce
Pigmented melanin
Epidermal dendritic (Langerhans) cells are
Macrophages that help activate immune system
Tactile (Merkel) cells are
Touch receptors
Stratum corneum
Most superficial layer; 20-30 layers of dead cells represented only by flat membranous sacs filled with keratin. Glycolipids in extra cellular space
Stratum granulosum
Three to five layers of flattened cells, organelles deteriorating; cytoplasm full of lamellated granules and keratohyaline granules
Stratum spinosum
Several layers of keratinocytes unified by desmosomes. Cells contain thick bundles of intermediate filaments made of pre-keratin
Stratum basale
Deepest epidermal layer; one row of actively mitotic stem cells; some Newley formed cells become part of the more superficial layers.
Journey from basal layer to surface takes
25-45 days
Stratum spinosum
Cells contain weblike system of intermediate prekeratin filaments attached to desmosomes. Interlock to support skin
What layer of the epidermis initiates keratinization
Stratum granulosum
Is three-quarters of the epidermal thickness and protects from abrasion and penetration, waterproofs, and is a barrier against biological, chemical and physical assaults
Stratum corneum
Is strong, flexible connective tissue. Cells include fibroblasts, macrophages, and occasionally mast cells and white blood cells
Dermis
The papillary layer of the dermis is made of
Loose connective tissue
The reticular layer of the dermis is made of
Dense connective tissue
What layer of the dermis has areolar connective tissue with collagen and elastic fibers and blood vessels
Papillary layer
Dermal papillae contain
Capillary loops
Meissners corpuscles
Free nerve endings
Capillary loops do what
Nourish the epidermis
Meissner’s corpuscles are
Sensory touch receptors