Chapter 5 Pt 2 Flashcards
Membrane Structure
o Phospholipd bilaye
o Fluid mosaic model
-Mosaic of proteins floats in or on the fluid lipid bilayer like boats on a pond
4 components of membranes
- Phospholipid bilayer
- Transmembrane proteins
- Interior protein between
- Cell surface markers
Phospholipid bilayer
o Fluid
o Hydrogen bonding of water holds the 2 layers together
o Individual phospholipids and unanchored proteins can move through membrane
Influences of fluidity
Saturated fatty acids make the membrane less fluid than unsaturated fatty acids
Warm temperatures make the membrane more fluid than cold temperatures
As temperature cool, membranes switch from a _____
fluid state to a solid state
Membranes must be _____ to work properly
Fluid
Membranes rich in _______ ____ ______ are more fluid
Unsaturated fatty acids
Cholesterol
Steroid alcohol added to membranes
o Warm temperature, cholesterol ______ movement of phospholipids
restrains
At cool temperatures cholesterol maintains fluidity by preventing _____ _______
tight packing
Peripheral proteins
Bound to the surface of the membrane
Integral proteins
Penetrate the hydrophobic core
Membrane proteins functions
Transporters Enzymes Cell-surface receptors Cell-surface identity markers Cell-to-cell adhesion proteins Attachments to the cytoskeleton
Membrane proteins Structure relates to _____
function
Anchoring molecules
-Modified lipids
=Integral membrane proteins
Modified lipids
Non polar region insert to the internal portion of the lipid bilayer
Chemical bonding domains linked directlhy to proteins
o Integral membrane proteins
-Span the lipid bilayer • Non polar interior • Polar exterior -Transmembrane domain • Spans the lipid bilayer • Hydrophobic amino acids arranged in a-helixs