Chapter 5 - Plasma Membranes Flashcards
Define compartmentalisation
The formation of separate membrane -bound organelles
Why are phospholipids suited as membranes?
Because their hydrophilic heads can interact with water
What does the fluid-mosaic model show?
That the phospholipids are free to move within the layer relative to each other
Membrane is flexible
Because proteins embedded in the bilayer vary in shape, size and position
What are intrinsic proteins?
Transmembrane proteins that are embedded through both layers of a membrane
Have aa w hydrophobic R-groups on external surfaces which interact w the hydrophobic core of the membrane
Give 4 examples of intrinsic proteins
Channel proteins
carrier proteins
glycoproteins
glycolipids
Why do we need compartmentalisation?
Because the metabolic reactions require different conditions (e.g. chemical gradients to be maintained)
Describe the function of a channel protein?
To provide a hydrophilic channel that allows the passive movement of polar mol. and ions down a concentration gradient through membranes
How are channel proteins held together?
Through the interactions between the hydrophobic core of membrane and hydrophilic R-groups on outside
What is the role of a carrier protein?
Helps in the passive transport (down conc grad) and active transport (against conc) into cells
Where are glycoproteins found?
Embedded in the cell surface membrane w attached carbohydrate chains of varying length and shape
What role do glycoproteins have?
Cell adhesion and act as receptors for chemical signals
How do glycoproteins help with cell signals?
When the chemical binds to the receptor it creates a response from the cell
Either direct response or set of a cascade of events
Give examples of when cell signalling is used with glycoproteins
Receptors for neurotransmitters at nerve synapses
Which protein can be both intrinsic and extrinsic?
Glycolipids
What is the difference between glycolipids and glycoproteins?
Glycolipids are lipids with carbohydrate attached whereas glycoprotein is a protein
What is the function of a glycolipid?
To act as cell markers or antigens, can be recognised by immune system as self