Chapter 5 - Linkage/Mapping Flashcards
violation of Mendel’s 2nd Law
genes linked on the same chromosome segregate together
the greater the distance between the genes,
the greater the chance of crossovers
crossovers occur at
prophase I of meiosis
independent assortment always gives
50% recombination
recombination frequency
recombinant strands per total strands progeny per meiosis
accurate map distances
less than 7 mu
why recombination frequency underestimates true map distance
double crossovers between two loci will restore at least some parental genotypes
coefficient of coincidence
the observed number of DCOs divided by the expected number of DCOS
interference equation
1 - CoC
interference definition
observed double crossover frequency differs from the expected double crossover frequency
positive interference
one crossover reduces the likelihood of a second simultaneous crossover