Chapter 4 - Gene Interaction Flashcards
epistasis definition
alleles of one gene make the phenotypic effects of the alleles of a different gene
incomplete penetrance
occurs when a dominant phenotype is not expressed even though an individual carries a dominant allele
pleiotropy
one gene thats affects many physiological processes throughout the life cycle
penetrance
frequency at which al allele manifests itself phenotypically within a population
expressivity
degree of phenotypic manifestation of a genotype in a particular individual
haploinsufficient
a wild type allele that is unable to support wild type function in heterozygous organisms (recessive wild type)
dihybrid phenotype ratio for recessive epistasis
9:3:4
dihybrid phenotype ratio for dominant epistasis
12:3:1
dihybrid phenotype ratio for duplicate recessive epistasis
9:7
genetic complementation
occurs when mutant organisms carry mutations of different genes that produce the same abnormal phenotype
complementation test (or cis-trans)
cross true-breeding mutant with same phenotype to each other
trans-complementation
if F1 is wild type, the mutations are not alleles of the same gene, so mutations in 2 different genes affect the same trait