Chapter 1 - Intro Flashcards

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1
Q

hereditary genetics

A
  • observing phenotypes in offspring to understand gene inheritance
  • tracing pedigrees of gene transmission within a family
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2
Q

population genetics

A

calculating allele frequencies to determine changes in gene pools

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3
Q

molecular genetics

A
  • generating plasmids from recombinant DNA

- studying DNA-protien interactions to understand gene regulation

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4
Q

Chargaff’s discoveries about base pair of DNA

A
  • DNA molecules contain similar numbers of A and T bases and G and C
  • proportions of A:T and G:C are similar within members of the same species
  • complementary base pairs
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5
Q

Watson and Crick findings from x-ray image of DNA

A

DNA is shaped like a helix, includes 10 base pairs per repeat, and has a consistent diameter

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6
Q

central dogma of biology

A

DNA is transcribed into RNA. RNA is translated into an amino acid sequence

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7
Q

Initiation (first step of transcription)

A
  1. RNA poly binds to group of transcription factors
  2. DNA helix unwinds
  3. RNA synthesis begins
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8
Q

Elongation (second step of transcription)

A
  1. DNA poly transverses the DNA template, adding complementary base pairs
  2. newly transcribed RNA transcript is proofread
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9
Q

termination (third step of transcription)

A
  1. RNA poly detaches from DNA
  2. RNA poly stops adding base pairs at a stop codon
  3. RNA transcript is released
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10
Q

transcription

A

takes place in the nucleus and produces mRNA

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11
Q

translation

A

takes place in ribosomes, produces a protein, and involves tRNA

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12
Q

characteristics required for heredity

A
  1. stable enough to store info for long periods
  2. able to replicate accurately
  3. capable of change to allow evolution
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13
Q

semiconservative replication

A

creates 2 new duplexes, one parental strand and one daughter strand

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14
Q

mRNA

A
  • transcribed from DNA
  • codons complement DNA
  • simple strand
  • broken down after translation
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15
Q

tRNA

A
  • used to translate mRNA
  • anticodons complement mRNA
  • clover-shaped look structure
  • reactivate after translation
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16
Q

transmission genetics

A

study of transmission of trains in successive generations

17
Q

evolutionary genetics

A

study of the origins of and genetic relationships between organisms, and evolution of genes and genomes

18
Q

molecular genetics

A

studies inheritance and variation of nucleic acids and proteins

19
Q

natural selection

A

differential reproductive success of members of a species, and forms that are best adapted will increase in a poplation

20
Q

migration

A

movement of members of a species from one population to another that rapidly alters allele frequencies

21
Q

mutation

A

the slow addition of allelic variants that increase the diversity of a population

22
Q

random genetic drift

A

random change of allele frequencies due to chance in rapidly mating populations