Chapter 5 - Integumentary System Flashcards
Integumentary system is composed of
Skin, hair, oil glands, sweat glands, nails, sensory receptors
Whats the largest organ of the body?
Skin - cutaneous membrane
Skin consists of 3 parts, what are they
Epidermis - superficial, thin, composed of epitherlial cells
Dermis - deeper layer, composed of connective tissue
Hyperdermis - subcutaneous later, consists of areolar and adipose tissue
Whats the purpose of the subcutaneous layer?
Storage layer for fat and contains large blood vessels that supply the skin
Contains nerve endings called lamellated pacinian corpuscles that are sensitive to pressure
Epidermis is composed of
Keratinized stratified squamous epithelium
Epidermis consists of 4 principal layers of cells:
Keratinocytes
Melanocytes
Intraepithelial macrophages
Tactile epithelial cells
What makes up 90% of epidermal cells
Keratinocytes
4-5 layers
Produce protein keratin
8% of the epiderma cells are
Melanocytes
Produce melanin
Long, slinder processes that extend between the keratinocytes
Melanin is what
a yellow-red or brown - black pigment that contributes skin color and absorbs damaging UV light
Intraepithelial macrophages are also called what and do what
Langerhans cells
Participate in immune responses mounted against microbes that invade the skin
Help recognize an antigen
Tactile epithelial cells
Contact the flattened process of a sensory neuron (nerve cell) - a structure called a tactile disc
These detect touch sensations
Epidermis has what 5 layers
Stratum basale Stratum spinosum Stratum granulosum Startum lucidum Stratum corneum
Stratum basale
Deepest layer
Cubodial or columnar keratinocytes
Stem cells
Stratum spinosum
Lies superficial to stratum basale
8-10 layers of many sided (polyhedral) keratinocytes
Provides strength and flexibility to the skin
Stratum granulosum
Middle part of the epidermis
3-5 layers of flattened keratinocytes that are undergoing apoptosis (programmed cell death)
Presence of keratin and membrane enclosed lamellar granules which release a lipid-rich secretion
This secretion regards loss of body fluids and entry of foreign materials
Stratum lucidum (clear cell layer)
Thick skin ares
Fingertips, palm, sole of foot
3-5 layers of flattened, clear, dead, keratinocytes containing lg amts of keratin
Stratum corneum
25-30 layers of flattened dead keratinocytes
Continuously shed and replaced
Contain mostly keratin
Protect deeper layers from injury and microbial invasion
What happens with constant exposure to friction
Callus
An abnml thickening of the stratum corneum
What is keratinization
As cells move one epithelial layer to the next, they accumulate more and more keratin
Dandurff
Shedding of an excessive amt of keratinized cells form the skin of hte scalp
Dermis is composed of
Connective tissue Collagen Elastic fibers Dermal papillae Blood capilaries Free nerve endings
The surface are of the dermis is increased by
Small fingerlike projections called the dermal papillae
The deeper part of the dermis consists of what
Dense irregular connective tissue
Consists of:
Collagen, elastic fibers, adipose cells, hair follicles, nerves, oil (sebaceous) glands, sweat glands
What does the combination of collagen and elastic fibers in the dermis do
Provide the skin with strength, extensibility, and elasticity
Extreme stretching of the skin can do what?
Produce small tears in the dermis causing striae or stretch marks on the skin surface
3 pigments that allow for skin colors are
Melanin
Hemoglobin
Carotene
Melanin is produced by what
Melanocytes in the epidermis
Stimulated by exposure to UV light
Loss of melanocytes = immune system malfunction where antibodies attack melanocytes
Skin cancer is caused by
Repeated exposure to UV light