Chapter 5: Energy Expenditure and Fatigue Flashcards
What is the substrate metabolism efficiency?
substrate energy
What is the percentage of substrate energy for ATP?
40%
What is the percentage of substrate energy for heat?
60%
heat production increases with what production?
energy
how can heat production increase with energy production?
- can be measured in a calorimeter
- water flows through walls
- body temperature increases water temperature
What are the Pros for measuring energy expenditure: direct calorimetry?
- accurate over time
- good for resting metabolic measurements
What are the Cons for measuring energy expenditure: direct calorimetry?
- expensive, slow
- exercise equipment adds extra heat
- sweat creates errors in measurements
- not practical or accurate for exercise
In indirect calorimetry, What is estimated total body energy expenditure based on?
O2 and CO2 produced
What does indirect calorimetry measure?
respiratory and gas concentrations
What is indirect calorimetry only accurate for?
steady-state oxidative metabolism
For indirect calorimetry, older methods of analysis are accurate but what?
slow
For indirect calorimetry, new methods are faster but what?
expensice
What does VO2 stand for?
volume of oxygen
What does VCO2 stand for?
volume of carbon dioxide
Explain VO2: volume of O2 consumed per minute.
- rate O2 consumption
- volume of inspired O2- volume of expired O2
Explain VCO2: volume of CO2 consumed per minute.
- rate CO2 consumption
- volume of expired CO2- volume of inspired CO2
What are the 6 calculations of VO2 and VCO2?
- volume of inspired air (Vi)
- volume of expired air (Ve)
- fraction of O2 in inspired air (FiO2)
- fraction of CO2 in inspired air (FiCO2)
- fraction of O2 in expired air (FeO2)
- fraction of CO2 in expired air (FeCO2)
What is the formula for oxygen consumption?
VO2= (Vi x FiO2) - (Ve x FeO2)
What is the formula for Carbon Dioxide produced?
VCO2= (Ve x FeCO2) - (Vi x FiCO2)
What are the oxygen consumption and carbon dioxide equations based on?
inspired volume= expired air volume
During Haldane Transformation, V of inspired O2 may not equal what?
V of expired CO2
During Haldane Transformation, V of inspired N2 equals what?
V of expired N2
Explain the Haldane Transformation.
- allows V of inspired air (unknown) to be directly calculated from V of expired air (known)
- based on constancy of N2 volumes
During Haldane Transformation, we measure concentration of O2 and CO2 in expired air why?
to calculate FeN2
FeN2= 1 - (FeO2 + FeCO2)
What is the SIMPLIFIED equation of Haldane Transformation?
VO2= (Ve) x {[1- (FeO2 + FeCO2)] x 0.265 - FeO2}
In the end of Haldane transformation, BTPS (body temperature, current atmospheric pressure, saturated with water vapor) is converted to what?
STPD ( standard temp (0degC) & pressure (760 mmHg), dry equivalent
During Respiratory Exchange Rate, explain the O2 usage.
O2 usage during metabolism depends on type of fuel being oxidized
- more carbon atoms in molecule = more O2 needed
- glucose (C6H12O6) < palmitic acid (C16H32O2)
Explain Respiratory Exchange Ratio (RER).
- ratio between rates of CO2 production, O2 usage
- allow to determine what % is energy coming from fat and carbs
What is the equation for RER?
RER= VCO2/ VO2
What requires more O2: Fat or Carbs?
FAT
What happens to fat and carbs if the intensity is increased?
fat decreases and carbs increases
1 liter of O2 equals to how many kcal?
5
What is metabolic rate?
Rate of energy use by body