Chapter 5: Energy and Life Flashcards
Energy
- The ability to do work
- Kinetic energy: motion
- Potential energy: stored energy
Thermodynamics
- The study of energy or heat changes
Chemical reactions
- Making and breaking of chemical bonds
1st Law of Thermodynamics
- Energy cannot be created or destroyed
- Energy flows in one direction and some of that energy is dissipated as heat
2nd Law of Thermodynamics
- Entropy: measure of the degree of disorder in a system
Substrate (reactants)
- Starting molecules of a chemical reaction
Products
- Molecules at the end of a reaction
Endergonic reactions
- product contains more energy than reactants
- require input of energy
- not spontaneous
Exergonic reactions
- produces products that contain less free energy than that produced by original reactants
- release energy
- can be spontaneous
Activation energy
- initial input of energy needed to start reaction, break bonds
Catalysis
- lowers the activation energy of a reaction
Enzymes
- catalysts used by cells to perform particular reactions
- usually proteins but can be nucleic acids
Induced fit model
- active site + reactant binding site = puzzle piece fit
Biochemical pathway
- catalyzed reactions occur together in sequence
Effect of temperature on enzymes
- as temp increases, reaction rate increases
- but, if temp gets too high, enzyme denatures and loses its shape and function
- optimal range for humans is 35-40° C
Effect of pH on enzymes
- optimal range for humans is 6-8
- except for stomach which is pH 2
Allosteric enzymes
- cells can control enzymes by altering their shape
- allosteric enzymes are affected by the binding of signal molecules
Feedback inhibition
- a form of enzyme inhibition where the product of a reaction acts as a repressor
Competitive inhibition
- binding of inhibitor to active site prevents reaction from occurring
- e.g., Lipitor
Noncompetitive inhibition
- inhibitor reduces activity of enzymes
- e.g., certain antibiotics
ATP
- Adenosine triphosphate
1. A sugar
2. An adenine nucleotide
3. A chain of 3 phosphate groups (energy is stored between the phosphate groups, they have same charge and don’t want to be near each other)
How is energy released from ATP?
- When the endmost phosphate group is broken off an ATP molecule
Equation for ATP breakdown
ATP –> ADP + Pi + energy
Coupled reactions
- occur when exergonic reactions are used to pay for the initiation of endergonic reactions
Oxidation-reduction reactions
- redox reactions
- electrons pass from atoms or molecules to one another
- involve transfer of energy because the electrons retain their potential energy