Chapter 5: Drug References Flashcards
Definition: package insert
FDA approved drug information. Only contains iformation approved by FDA
does not include off label uses or cost
Definition: Boxed Warnings
- the strictest warnning
- alerts prescribers of risk of death or permanent disability
Definition: contraindications
- if a pt has a contraindication, the drug canNOT be used in taht patient
- risk outweights possible benefit
Definition: warnings and precautions
include serious reactions that can result ind eath, hospitalziation, medical intervention, disability or teratogenicity
Definition: adverse reactiosn
refers to undesirable, uncomfortable or dangerous effects
Labeling requirements for OTC
- active ingredients
- uses for the product
- speific warnings, including when the drug should NOT be used
- side effects
- dosage insturctions
- inactive ingredients
Anticoagulation guidelines
Guidelines from the American College of Chest Physicians (CHEST guidelines)
A. fib, VTE
Cardiovascular disease guidelines
Guidelines from the American College of Cardiology/American Heart Association (ACC/AHA)
- ACS
- A. fib
- HF
- High cholesterol
- HTN
Diabetes guideliens
- American Association of Clinical Endocrinologists (AACE)
- American Diabetes Association (ADA)
Infectious disase guidelines
- Infetious Diseases Society of America (IDSA)
- HIV/AIDS: US Dept of Health and Human Services (clincalinfo.hiv.gov)
- Sexually Transmitted Infections: Centers for Disease Control (CDC)
Sanford Guide to Antimicrobial Therapy (Reference)
Oncology guideliens
- American Society of Clinical Oncology (ASCO)
- National Comprehensive Cancer Network (NCCN)
Pediatrics guidelines
The American Academy of Pediatrics (AAP)
References:
- NeoFax and Pediatrics
- Pediatric & Neonatal Lexi-drugs
- Red Book
- Harriet Lane Handbook
- KIDS List (PIM’s for kids)
Pregnancy/Women’s Health guidelins
The American COllege of Obstetricians and Gyenocologists (ACOG)
References
- Briggs’ Drugs in Pregnagny and Lactation
- CDC
- Hale’s Medications and Mother’s Milk
- LactMed
Psychiatric conditions guideliens
- AMerican Psychiatric Association (APA) Diagnositc and Statistical Manual of Mental disorders (DSM)
Pulmonary conditions guidelines
- Asthma: Global Initiative for Asthma (GINA)
- COPD: Global Initiative for COPD (GOLD)
Kidney diseases guidelines
KDIGO
Vaccines guidelines
- Advisory Committee on Immunization Practices (ACIP) - updates published in the Morbidity and Mortality Weekly Report (MMWR)
- Centers for DIsease Control (CDC)
FDAble
FDA serachable database of ADR caused by medicines, vaccines, devices, tobacco products, and dietary supplements
- MedWatch: FDA’s Adverse Event Reporting System (FAERS)
- Vaccine Adverse Event Reporting SYstem (VAERS)
Compounding references
- Allen’s The Art, Science, and Technology of Pharmaceutical Compounding
- Safety Data Sheets
- USP 795: non-sterile
- USP 797: Sterile
- USP 800: Hazardous
- USP NF: monographs for drug sustances, dosage forms, compounded preparations and expients
Merck Index
databsase of monographs for chemicals, drugs, adn biologicals
RED BOOK
micromedex resource on drug priceing
where to look for information on drug shortges
- ASHP current drug shortages
- FDA drug shortages
reference for med use in geriatrcs
American Geriatric Society (AGS) Beers Criteria
CDC Pink Book
epidemiology and prevention of vaccine preventable disases
Where to find international drug information
- Index Nomium: international drug directory
- Martindale: the complete drug referece
where to find investigational drugs
clinicaltrials.gov
reference for IV drug compatibility and stability
- ASHP Handbook on Injectable Drugs
- King Guide to Parenteral Admixtures
- Trissel’s 2 CLinical Pharmaceutics Database
Where to report med errors
Institute for Safe Medication Practices (ISMP) Medication Errors Reporting Program)
NIOSH
list of antineoplastic and other hazardous drugs
Reference for natural products and alternative medicine
NatMed
reference for pharmacology
Goodman and Gilman’s The Pharmacological Basis of Therapeutics
reference fo poisoning and toxicology
- Lexi-Tox
- Micromedex
veterinary reference
Plumb’s
“color” drug references
- Red Book, Pharmacy: drug pricing
- Red Book, Pediatrics: summaries of peds ID, ABX, and vaccine info
- Orange Book (FDA): approved drugs that can be interchaged with generics
- Yellow Book (CDC): info on interational travel, vaccines, and ppx
- Green Book (FDA): info on approved annimal drug products
- Purple Book (FDA): list of biologicals and biosimilars
- Pink Book (CDCC): epidemiology and vaccine preventable diseases
- Pink Sheet (Pharma Intelligence): news reports on regulatory, legislative, legal and business developments
Consumer resources
- CDC: ID, immunizations, and travel
- Drugs.com and RxList
- Mayo Clinic
- Medline Plus
- WebMD: has pill identifier and interaction checker