Chapter 5- Cellular respiration Flashcards

1
Q

3 jobs of cellular respiration

A
  1. Breaks down carbohydrates, lipids, and proteins
  2. Converts energy that is liberated into ATP
  3. Allows the cell to do work
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2
Q

What is cellular respiration

A
  • Collection of metabolic reactions within cells that breaks down food molecules (catabolic reactions) to produce ATP
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3
Q

ATP

A

form of chemical energy required for thousands of biosynthetic reactions (anabolic reactions) taking place within the cell

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4
Q

Where is energy coming from?

A

the sun

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5
Q

Oxidation-Reduction (Redox) Reactions

A

Chemical reactions in which electrons are transferred from one atom or molecule to another

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6
Q

LEO GER

A

loss of electrons= oxidation
gain of electrons = reduction

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7
Q

Electron Sharing

A

Sometimes only the degree of electron sharing in covalent bonds changes (a relative loss or gain of electrons)

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8
Q

Oxidation

A

partial or full loss of e- to a substance

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9
Q

Reduction

A

partial or full gain of e- to a substance

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10
Q

Redox reaction

A

coupled reactions: The oxidation reaction and the reduction reaction occur simultaneously

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11
Q

Cellular respiration formula

A

C6H12O6 + 6O2 –> 6CO2 +6H2O + ENERGY

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12
Q

3 stages of cellular respiration

A
  1. glycolysis
  2. pyruvate oxidation and the citric acid cycle
  3. oxidative phosphorlation
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13
Q

Where do glycolysis, pyruvate oxidation and citric acid cycle, and oxidative phosphorylation occur?

A

glycolysis - cytosol
Pyruvate oxidation and the citric acid cycle- mitochondria
Oxidative phosphorylation- mitochondria

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14
Q

where do most cellular respiration reactions occur

A

mitochondria

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15
Q

does glycolysis require O2

A

no

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16
Q

how many reactions in glycolysis

A

series of 10 chemical reactions, each catalyzed by a different enzyme

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17
Q

What does glycolysis convert

A

converts glucose (6 carbons) in to 2 pyruvate molecules (3 carbons each)

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18
Q

Phases of glycolysis

A

Phase I: Glucose → Fructose 1,6 Bisphosphate
Phase II: Fructose-1,6-Bisphosphate → Glyceraldehyde 3-phosphate
Phase III: glyceraldehyde 3-phosphate → Pyruvate

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19
Q

Phase I of glycolysis

A
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20
Q

Phase II of glycolysis

A
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21
Q

Phase III of glycolysis

A
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22
Q

Substrate level phosphorylation

A

a phosphate group is transferred from a high-energy donor directly to ADP, forming ATP

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23
Q

When is most of the ATP produced duringing cellular respiration

A

oxidative phosphorlation

24
Q

When is most of the ATP produced during cellular respiration

A

oxidative phosphorylation

25
What happens in the mitochondrial membrane
- electron transfer - ATP synthesis by ATP synthase
26
What happens in the mitochondrial matrix
pyruvate oxidation and the citric acid cycle
27
Phosphofructokinase
catalyzes the second ATP-consuming step of the pathway
28
Pyruvate Oxidation
Pyruvate (3C) is oxidized to an acetyl group (2C) * CO2 is produced * Electrons removed are accepted by (or used to reduce) NAD+ to form NADH * Acetyl group linked to Co-Enzyme A (CoA)
29
is pyruvate oxidation aerobic or anaerobic?
aerobic
30
What does each pyruvate molecule produce
1 acetyl group 1 NADH 1 CO2
31
What does pyruvate oxidation link
glycolysis and the citric acid cycle
32
what happens to the acetyl group after pyruvate oxidation
Acetyl groups attached to coenzyme A * Delivered to citric acid cycle
33
Citric Acid cycle
Acetyl groups completely oxidized to CO2 * Electrons removed in a series of oxidations * Accepted by NAD+ or FAD (which get reduced to NADH and FADH2) * Some ATP made by substrate-level phosphorylation
34
Produced from the citric acid cycle
Each acetyl group that enters the cycle and gets oxidized produces * 2 CO2 * 1 ATP (by substrate-level phosphorylation) * 3 NADH * 1 FADH2
35
What do electrons pass from in the ETC
NADH and FADH2 --> O2
36
What does the ETC include
- 4 protein complexed 2 smaller shuttle carriers
37
how do electrons move along the ETC
spontaneously
38
what protein complexes are in the Respiratory ETC
3 major protein complexes I, II, Iv
39
What do the respiratory ETC protein complexes do
* Pump H+ from Matrix to IMS * Contain prosthetic groups that cycle between reduced and oxidized states
40
What do the electrons do in the respiratory ETC
* Depleted of energy * Delivered to oxygen as final electron acceptor
41
Chemiosmotic synthesis of ATP
involves the ATP synthase complex, which uses the energy of the proton gradient to catalyze the synthesis of ATP.
42
Why does fermentation occur
In eukaryotic cells, low oxygen levels result in fermentation
43
What is fermentation
the pathway of respiration that oxidizes fuel molecules in the absence of oxygen
44
what are the two types of fermentation
lactate fermentation and alcohol fermentation
45
where does lactic acid fermentation occur
animals and bacteria
46
how is lactic acid fermentation produced?
electrons from NADH are transferred to pyruvate to produce lactic acid and NAD+
47
Where does alcohol fermentation occur?
plants and fungi
48
how does alcohol fermentation happen?
Electrons from NADH are transferred to pyruvate to produce ethanol and NAD+
49
Facultative aerobes:
Can grow in presence of oxygen and can grow using fermentative pathways
50
is oxygen dangerous
yes, it can be a ROS (reactive oxygen species) - superoxide and peroxide - strong oxidizing agents
51
Defence against ROS
* Antioxidant defence system * Enzymes * Superoxide dismutase and catalase * Nonenzymes * Antioxidants: vitamin C and vitamin E
52
In eukaryotes what is the terminal electron acceptor
oxygen
53
what does aerobic respiration happen in
prokaryotes - bacteria eukaryotes - plants
54
How much ATP is required for glycolysis (input)
2
55
At the end of glycolysis, the energy from glucose has been stored in
2 pyruvate 2 ATP (NET) 2 NADH