Chapter 5-8 Flashcards
1
Q
IgG mediated disease
A
involves extravascular hemolysis binds RBC in WARM temp. RBC consumed by mps results in spherocytes
2
Q
IgG mediated disease associated with
A
SLE, CLL and DRUGS-penicillin and cephalosporin
3
Q
IgM mediated disease
A
involves intravascular hemolysis Abs attach to RBCs in COLD temp.
4
Q
IgM is associated with
A
mycoplasma pneumoniae & Mono
5
Q
diagnose IgM- most impt for IHA
A
direct coombs test confirms presence of Abs on RBC already coated with abs= MOst important test for IHA
6
Q
malaria
A
infects RBC and liver with plasmodium via ANOPHELES MOSQUITO
7
Q
parvoB19
A
infects progenitor RBCs stops erythropoiesis
8
Q
aplastic anemia
A
pancytopenia and low reticulocyte
9
Q
Tx Aplastic anemia
A
bone marrow aspirate of Cd15
