Chapter 5 Flashcards
What is a conformational change
Change in structure
What causes ions to cross the membrane
[Gradient] and electrical gradient
Which way do ions move toward like or opposite charges
Toward opposite charges
What is polarization
Separation of charges
What does depolarized mean
Becoming less polarized
What does hyperpolarize mean
Becoming more charged
Which way do pumps move ions with or against the electric/[gradients]
Against gradients
Do pumps have a pore
No
True or False:
Ions attract water
True
What are the 2 ways ion channels are selective
- Size of pore
2. Selectivity filter
What size ions attract more water smaller or larger ions
Smaller ions
What is bigger with a water shell Na+ or K+ and why
Na+ due to smaller ion size
How does selectivity filtering work
Amino acids in the pore that attract specific ions which causes the water shell to be shed and Na+ moves through and is propelled into cell and regains water shell
What is the patch clamp technique
Take a glass pipette with ions in it and fill it with solution then place it onto cell membrane so 1 ion channel is inside of it and then pull pack on pipette making seal then release ions
What is the patch clamp technique used for
Detecting if ions are moving in or out of cells