Chapter 5 Flashcards
Excitotoxic lesion
Uses excitatory amino acid to target more specific spot to kill neurons rather than also passer by’s
Experiment ablation “lesion study”
Removal of portion of brain
Functions no longer capable are ones that region controls
Cell body stains make it possible for
Identify nuclear masses in the brain
Anterograde labeling method
Identifies axons leaving particular region and the terminal buttons of the axons with PHA-L
Retrograde labeling method
Identify location of neurons whose axons terminate in particular region using fluorogold
Transneuronal tracing method
Shows connections through synapses
Chronological Order
Made over an extended period of time after animal recovers from surgery
Acute recording
Short period where animal is anesthetized
Sensory pathways
Seldom behavioral observations
Microelectrodes
Very fine electrode to record activity of individual neurons
Single-unit recording
Recording of electrical activity of a single neuron
Macroelectrode
Electrode used to record large number of neurons in a region
Amygdala
Compromises components of fear
NMDA receptor
Is ligand dependent and voltage dependent
What blocks LTP in hippocampus
Drug blocking NMDA receptor