Chapter 5

Question 1

is a general term for agents that bind to
cholinoceptors (muscarinic or nicotinic) and prevent the effects of acetylcholine (ACh) and other cholinergic agonists.

a. cholinergic agonist
b. cholinergic antagonist

Answer 1

b. cholinergic antagonist

Question 1

parasympathetic innervation are thus, interrupted by these agents, and
the actions of sympathetic innervation are left unopposed.

a. cholinergic agonist
b. cholinergic antagonist

Answer 1

b. cholinergic antagonist

it is also called parasympatholytic

Question 2

These drugs are used as skeletal muscle relaxants in surgical
anesthesia and as agents to facilitate intubation in surgical and critical
care patients.

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

Answer 2

c. neuromuscular blocker

Question 3

aclidinium

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

Answer 3

a. antimuscarinic agents

Question 4

atropine

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

Answer 4

a. antimuscarinic agents

Question 5

benztropine

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

Answer 5

a. antimuscarinic agents

Question 6

cyclopentolate

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

Answer 6

a. antimuscarinic agents

Question 7

darifenacin

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

Answer 7

a. antimuscarinic agents

Question 8

fesoterodine

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

Answer 8

a. antimuscarinic agents

Question 9

glycopyrrolate

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

Answer 9

a. antimuscarinic agents

Question 10

hyoscyamine

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

Answer 10

a. antimuscarinic agents

Question 11

ipratropium

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

Answer 11

a. antimuscarinic agents

Question 12

oxybutynin

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

Answer 12

a. antimuscarinic agents

Question 13

scopolamine
a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

Answer 13

a. antimuscarinic agents

Question 14

solifenacin

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

Answer 14

a. antimuscarinic agents

Question 15

tiotropium

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

Answer 15

a. antimuscarinic agents

Question 16

tolterodine

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

Answer 16

a.antimuscarinic agents

Question 17

trihexyphenidyl

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

Answer 17

a. antimuscarinic agents

Question 18

tropicamide

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

Answer 18

a. antimuscarinic agent

Question 19

trospium

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

Answer 19

a. antimuscarinic agents

Question 20

nicotine

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

Answer 20

b. ganglionic blocker

Question 21

cisatracurium

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

Answer 21

c. neuromuscular blocker

Question 22

mivacurium

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

Answer 22

c. neuromuscular blocker

Question 23

Pancuronium

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

Answer 23

c. neuromuscular blocker

Question 24

rocuronium a. antimuscarinic agents b. ganglionic blocker c. neuromuscular blocker

Answer 24

c. neuromuscular blocker

Question 25

succinylcholine a. antimuscarinic agents b. ganglionic blocker c. neuromuscular blocker

Answer 25

c. neuromuscular blocker

Question 26

vecuronium a. antimuscarinic agents b. ganglionic blocker c. neuromuscular blocker

Answer 26

c. neuromuscular blocker

Question 27

these drugs block the few exceptional sympathetic neurons that are cholinergic, such as those innervating the salivary and sweat glands. a. antimuscarinic agents b. ganglionic blocker c. neuromuscular blocker

Answer 27

a. antimuscarinic agents

Question 28

Because they do not block nicotinic receptors, have little or no action at skeletal neuromuscular junctions (NMJs) or autonomic ganglia. a. antimuscarinic agents b. ganglionic blocker c. neuromuscular blocker

Answer 28

a. antimuscarinic agents [Note: A number of antihistamines and antidepressants (mainly tricyclic antidepressants) also have antimuscarinic activity.]

Question 29

is a tertiary amine extracted from belladonna alkaloid a. Aclidinium b. Atropine c. Benztropine

Answer 29

b. Atropine Atropine acts both centrally and peripherally. duration of action : 4 hours The greatest inhibitory effects are seen in bronchial tissue, salivary and sweat glands, and the heart

Question 30

dilation of pupil a. mydriasis b. cycloplegia

Answer 30

a. mydriasis

Question 31

inability to focus for near vision a. mydriasis b. cycloplegia

Answer 31

b. cycloplegia

Question 32

blocks muscarinic activity in the eye, resulting in mydriasis (dilation of the pupil), unresponsiveness to light, and cycloplegia (inability to focus for near vision). a. Aclidinium b. Atropine c. Benztropine

Answer 32

b. Atropine

Question 33

In patients with angle-closure glaucoma, intraocular pressure may rise dangerously. a. Aclidinium b. Atropine c. Benztropine

Answer 33

b. Atropine

Question 34

as the active isomer, L-hyoscyamine a. Aclidinium b. Atropine c. Benztropine

Answer 34

b. Atropine

Question 35

can be used as an antispasmodic to reduce activity of the Gl tract. a. Aclidinium b. Atropine c. Benztropine

Answer 35

b. Atropine

Question 36

what are probably the most potent antispasmodic drugs available. a. Aclidinium b. Atropine c. scopolamine

Answer 36

b and c.

Question 37

is Atropine effective in the treatment of ulcer? a. yes b. no

Answer 37

b. no Although gastric motility is reduced, hydrochloric acid production is not significantly affected. note:Doses of atropine that reduce spasms also reduce saliva secretion, ocular accommodation, and urination. These effects decrease compliance with atropine.

Question 38

At low doses, the predominant effect is a slight decrease in heart rate. a. Aclidinium b. Atropine c. scopolamine

Answer 38

b. atropine

Question 39

Higher doses of atropine cause a progressive increase in heart rate by blocking M2 receptors on the sinoatrial node. a. Aclidinium b. Atropine c. scopolamine

Answer 39

b. Atropine

Question 40

blocks muscarinic receptors in the salivary glands, producing dryness of the mouth (xerostomia). a. Aclidinium b. Atropine c. scopolamine

Answer 40

b. Atropine

Question 41

dryness in the mouth a. mydriasis b. cycloplegia c. xerostomia

Answer 41

c. xerostomia

Question 42

when this drug is applies topically it exerts both mydriatic and cycloplegic effects, and it permits the measurement of refractive errors without interference by the accommodative capacity of the eye. a. Aclidinium b. Atropine c. scopolamine

Answer 42

b. atropine

Question 43

what are the drugs that have largely replaced atropine due to prolonged mydriasis observed with atropine a. cyclopentolate b. darifenacin c. tropicamide

Answer 43

a nd c . [Note: Phenylephrine or similar a-adrenergic drugs are preferred for pupillary dilation if cycloplegia is not required.]