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kaps > Chapter 5 > Flashcards

Chapter 5 Flashcards

1
Q

is a general term for agents that bind to
cholinoceptors (muscarinic or nicotinic) and prevent the effects of acetylcholine (ACh) and other cholinergic agonists.

a. cholinergic agonist
b. cholinergic antagonist

A

b. cholinergic antagonist

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1
Q

parasympathetic innervation are thus, interrupted by these agents, and
the actions of sympathetic innervation are left unopposed.

a. cholinergic agonist
b. cholinergic antagonist

A

b. cholinergic antagonist

it is also called parasympatholytic

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2
Q

These drugs are used as skeletal muscle relaxants in surgical
anesthesia and as agents to facilitate intubation in surgical and critical
care patients.

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

A

c. neuromuscular blocker

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3
Q

aclidinium

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

A

a. antimuscarinic agents

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4
Q

atropine

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

A

a. antimuscarinic agents

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5
Q

benztropine

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

A

a. antimuscarinic agents

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6
Q

cyclopentolate

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

A

a. antimuscarinic agents

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7
Q

darifenacin

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

A

a. antimuscarinic agents

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8
Q

fesoterodine

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

A

a. antimuscarinic agents

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9
Q

glycopyrrolate

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

A

a. antimuscarinic agents

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10
Q

hyoscyamine

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

A

a. antimuscarinic agents

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11
Q

ipratropium

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

A

a. antimuscarinic agents

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12
Q

oxybutynin

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

A

a. antimuscarinic agents

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13
Q

scopolamine
a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

A

a. antimuscarinic agents

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14
Q

solifenacin

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

A

a. antimuscarinic agents

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15
Q

tiotropium

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

A

a. antimuscarinic agents

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16
Q

tolterodine

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

A

a.antimuscarinic agents

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17
Q

trihexyphenidyl

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

A

a. antimuscarinic agents

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18
Q

tropicamide

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

A

a. antimuscarinic agent

19
Q

trospium

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

A

a. antimuscarinic agents

20
Q

nicotine

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

A

b. ganglionic blocker

21
Q

cisatracurium

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

A

c. neuromuscular blocker

22
Q

mivacurium

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

A

c. neuromuscular blocker

23
Q

Pancuronium

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

A

c. neuromuscular blocker

24
Q

rocuronium

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

A

c. neuromuscular blocker

25
Q

succinylcholine

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

A

c. neuromuscular blocker

26
Q

vecuronium

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

A

c. neuromuscular blocker

27
Q

these drugs block the
few exceptional sympathetic neurons that are cholinergic, such as those
innervating the salivary and sweat glands.

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

A

a. antimuscarinic agents

28
Q

Because they do not block
nicotinic receptors, have little or no action at skeletal neuromuscular junctions
(NMJs) or autonomic ganglia.

a. antimuscarinic agents
b. ganglionic blocker
c. neuromuscular blocker

A

a. antimuscarinic agents

[Note: A number of antihistamines and
antidepressants (mainly tricyclic antidepressants) also have antimuscarinic activity.]

29
Q

is a tertiary amine extracted from belladonna alkaloid

a. Aclidinium
b. Atropine
c. Benztropine

A

b. Atropine

Atropine acts both centrally
and peripherally.

duration of action : 4 hours

The greatest inhibitory effects
are seen in bronchial tissue, salivary and sweat glands, and the heart

30
Q

dilation of pupil

a. mydriasis
b. cycloplegia

A

a. mydriasis

31
Q

inability to focus for near vision

a. mydriasis
b. cycloplegia

A

b. cycloplegia

32
Q

blocks muscarinic activity in the eye, resulting
in mydriasis (dilation of the pupil), unresponsiveness to light,
and cycloplegia (inability to focus for near vision).

a. Aclidinium
b. Atropine
c. Benztropine

A

b. Atropine

33
Q

In patients
with angle-closure glaucoma, intraocular pressure may rise
dangerously.

a. Aclidinium
b. Atropine
c. Benztropine

A

b. Atropine

34
Q

as the active isomer,
L-hyoscyamine

a. Aclidinium
b. Atropine
c. Benztropine

A

b. Atropine

35
Q

can be used as an
antispasmodic to reduce activity of the Gl tract.

a. Aclidinium
b. Atropine
c. Benztropine

A

b. Atropine

36
Q

what are probably the most
potent antispasmodic drugs available.

a. Aclidinium
b. Atropine
c. scopolamine

A

b and c.

37
Q

is Atropine effective in the treatment of ulcer?

a. yes
b. no

A

b. no

Although gastric motility is reduced, hydrochloric acid production is not significantly
affected.

note:Doses of atropine that reduce spasms also reduce
saliva secretion, ocular accommodation, and urination. These
effects decrease compliance with atropine.

38
Q

At low doses, the predominant effect is a slight decrease in
heart rate.

a. Aclidinium
b. Atropine
c. scopolamine

A

b. atropine

39
Q

Higher doses of atropine
cause a progressive increase in heart rate by blocking M2
receptors on the sinoatrial node.

a. Aclidinium
b. Atropine
c. scopolamine

A

b. Atropine

40
Q

blocks muscarinic receptors in the salivary glands, producing dryness of the mouth (xerostomia).

a. Aclidinium
b. Atropine
c. scopolamine

A

b. Atropine

41
Q

dryness in the mouth

a. mydriasis
b. cycloplegia
c. xerostomia

A

c. xerostomia

42
Q

when this drug is applies topically it exerts both mydriatic and
cycloplegic effects, and it permits the measurement of refractive errors without interference by the accommodative capacity of the eye.

a. Aclidinium
b. Atropine
c. scopolamine

A

b. atropine

43
Q

what are the drugs that have largely replaced atropine due to prolonged mydriasis
observed with atropine

a. cyclopentolate
b. darifenacin
c. tropicamide

A

a nd c

. [Note: Phenylephrine or similar a-adrenergic drugs are
preferred for pupillary dilation if cycloplegia is not required.]

44
Q
A

kaps (16 decks)

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