chapter 5 Flashcards
integumentary system
Name 3 external functions of the skin.
Regulating body temperature
Protection
Excretion
Name 4 internal functions of the skin.
Sensation
Immunity
Blood reservoir
vitamin D synthesis
Name the 3 general layers of the skin
Epidermis
Dermis
Hypodermis
Describe the epidermis.
Top layer
Keratinized, stratified squamous
Avascular
Define epidermal growth factor
Protein hormone that stimulates growth and repair.
Name the 4 cells of the epidermis.
Keratinocytes
Melanocytes
Langerhans cells
Merkel cells
What are the layers of the skin (most superficial to most deep).
s. corneum
s. lucidum
s. granulosum
s. spinosum
s. basale
What is the function of keratinocytes?
Make waterproofing keratin protein.
What is the function of melanocytes?
Make melanin pigment protein.
What is the function of Langerhans cells?
Immune system activator
Skin dendritic cells
Migrate from bone marrow
What is the function of Merkel cells (aka: Merkel discs)?
They are also known as:
Where are they located?
Touch/light pressure receptors
Located in deep part of epidermis
Mechanoreceptors and Cutaneous receptors
Describe the s. corneum.
20-30 layers of flat, dead keratinized cells
cells slough off
replaced from below
Describe the s. lucidum.
3-5 layers of clear cells
extra protection on palms and soles of feet.
Describe the s. granulosum.
3-5 layers of cells
state of degeneration
Describe the s. spinosum.
8-10 layers of cells
mostly keratinocytes connected by desmosomes
Describe the s. basale.
“germinativum” layer
ONE single layer of stem cells
active mitosis forms keratinocytes and melanocytes
Describe the dermis.
Below epidermis
Connective tissue w/ collagen and elastic fibers
Blood vessels (vascular)
Nerves, glands, and hair follicles
Cells have an ECM
Name the cells found in the dermis and their functions.
Fibroblasts
Macrophages
Adipocytes
Fibroblasts: Make connective protein fibers
Macrophages: immune function
Adipocytes: fat cells
What are the 2 regions of the dermis?
Papillary dermis
Reticular dermis
What tissue is found in the papillary dermis?
Areolar connective (loose).
What are 2 important features of the papillary dermis?
Dermal papillae
Meissner’s corpuscles
Bumpy “velcro”
Ridges create fingerprints
Dermal papillae
Tactile sensory receptors for touch and pressure
Meissner’s corpuscles
What tissue is found in the reticular dermis?
Dense, irregular connective tissue
Collagen and elastic fibers
What is an important structure found in the reticular dermis?
Pacinian corpuscles
Sensory receptors for deeper pressure
Pacinian corpuscles