Chapter 45 Flashcards

1
Q

In order to completely destroy a virus you also have to destroy

A

Host cell

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2
Q

What are the 4 ways viruses enter the body

A

Inhale
Ingest
Placenta
Inoculation

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3
Q

How to antiviral drugs work

A

Stop the virus from replicating

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4
Q

Antiviral drugs treat what

A

Any virus other than HIV

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5
Q

Antiretroviral drugs treat what

A

HIV

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6
Q

What antiviral med is used to treat Shingles

A

Acyclovir
Zostavax

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7
Q

What antiviral drug treats influenza A

A

Amantadine Hydrochloride

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8
Q

What antiviral cannot be given to lactating women or children younger than 12

A

Amantadine Hydrochloride

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9
Q

Adequate hydration to prevent crystalluria is needed for which antiviral

A

Acyclovir

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10
Q

Ganciclovir Hydrochloride is dose limited by what

A

Bone marrow suppression

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11
Q

What antiviral drug treats CMV

A

Ganciclovir Hydrochloride

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12
Q

What antiviral drug is used for Influenza A and B

A

Oseltamivir phosphate
Zanamivir

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13
Q

What form does oseltamivir come in

A

Oral

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14
Q

What form does zanamivir come in

A

Inhaled powder

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15
Q

Which antiviral drug for influenza A and B can be used prophylactically

A

Oseltamivir phosphate

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16
Q

What antiviral drug treats hepatitis C

A

Ribavirin

17
Q

What antiviral drug is used for infants with RSV

A

Virazole

18
Q

What antiviral drug is contraindicated in pregnant women and their sexual partner

A

Ribavarin

19
Q

Where can HIV be found

A

Blood
Tears
Sweat
Saliva
Urine

20
Q

How many stages does the HIV infection have

A

4

21
Q

Stage 1 HIV

A

Asymptomatic. Swollen lymph nodes

22
Q

Stage 2 HIV

A

Swollen lymph nodes, fever, rash, night sweats, weight loss of less than 10%

23
Q

Stage 3 HIV

A

Weight loss greater than 10% drop in CD4

24
Q

Stage 4 HIV

A

Often leads to death

25
Q

What does drug treatment of HIV do

A

Slows progression of infection

26
Q

What is usually the cause of death for patients with HIV

A

Opportunistic infections

27
Q

How can you evaluate if antiretroviral drugs are working

A

CD4 should be up, viral count should be down

28
Q

What are the 5 classes of antiretroviral drugs

A

Reverse transcriptase inhibitors
Protease inhibitors
Fusion inhibitor
Entry inhibitor
Integrate inhibitor

29
Q

Does limiting effect of Zidovudine is

A

Bone marrow suppression

30
Q

Zidovudine is often given with what to decrease risk of bone marrow suppression

A

Didanosine

31
Q

What will be given to healthcare workers if they are exposed to HIV by needle stick injury

A

Tenofovir and Lamivudine and Raltegravir