Chapter 44: Animal Development Flashcards
Animal development
transformation from a single egg, zygote (diploid [2n] fertilized egg) via cell division, cell movement, cell specialization, pattern formation and apoptosis
What are the stages of development?
cell division–>cell expansion–>growth–>cell differentiation–>creation of tissue–>creation of organs
What are the 4 processes of development?
- determination
- Differentiation
- Morphogenesis
- Growth
Differentiation
the process by which different types of cells arise
Morphogenesis
organization and spatial distribution of differentiated cells
Growth
increase in body size by cell division and expansion
What are the ways in which morphogenesis occurs?
cell division, cell expansion, cell movements, apoptosis
Cell fate
which type of tissue the cell will ultimately become. cell fate is usually determined quite early
Fertilization
gametes, sex cells
Haploid
one set of chromosomes
Diploid
two sets of chromosomes
Gametes are produced when?
meiosis
how do the gametes get their chromosomes?
each parent contributes a set
How is zygote produced?
fusion of gametes
What is the human egg protected by?
cumulus and zona pellucida
what does fertilization do?
- blocks entry of additional sperm
- stimulates ion fluxes across membranes
- changes pH of the egg
- increases egg metabolism and protein synthesis
- initiates cell division
what is contained in eggs
large, well stocked with organelles, nutrients, transcription factors, and mRNA
Cumulus
keeps out unhealthy sperm
What happens during fusion?
2 pronuclei lose their nuclear membranes and fuse together to form diploid zygote
Vegetal hemisphere
lower half of egg, where nutrients are concentrated
Animal hemisphere
opposite end of the egg, has pigments and contains nucleus
Cleavage
blastula formation, cleavage in mammals is unique, specific blasters generate specific tissues and organs
Gastrulation
three germ layer formation
Organogenesis
formation of an organ system
Neurulation
formation of a nervous system
Mosaic development is
determinate
Regulated development is
indeterminate
Cleavage
early cell divisions with no cell growth. embryo becomes a solid ball of small cells.
Blastocoel
a central fluid-filled cavity that forms in the ball
Blastula
developed embryo
Blastomeres
the cells of the blastula
complete cleavage
eggs with little yolk
incomplete cleavage
occurs in eggs with a lot of yolk when cleavage furrows don’t penetrate
Discoidal cleavage
embryo forms as a blastodisc that sits on top of the yolk
Superficial cleavage
variation of incomplete cleavage in insects
Syncytium
cell with many nuclei
Why is there little increase in overall volume during cleavage?
because the blastomeres become progressively smaller
What influences cleavage?
amount of yolk, orientation of mitotic spindle,
Blastocyst
a dense inner cell mass on top of a hollow blastocoel, surrounded by a trophoblast
Mammalian cleavage is slow or fast?
slow and asynchronous
what happens when the zygote reaches the 8 cell stage?
blastomeres change shape and maximize contact with one another to form a tight ball