Chapter 4: Sections 4.2, 4.3a, 4.3b: Structure of Plasma Membrane & Passive Transport Flashcards
List lipid components of the plasma membrane
Plasma membrane
Phospholipids
Cholesterol
Glycolipids
Function of plasma membrane
Regulates the movements of most substances in and out of the cell.
Function of phospholipids
Have polar “heads” and two hydrophobic “tails.” Prevents the plasma membrane from dissolving and allows small, nonpolar substances to penetrate w/o assistance
Function of Cholesterol
Strengthens the membrane and stabilizes the membrane against temperature extremes
Function of glycolipids
Help to form glcocalyx, the “coating of sugar” on the cell’s surface
Function of phospholipid bilayer
Ensures that cytosol and fluid surrounding cells remain separate.
Function of membrane proteins
Compose half of the plasma membrane by weight. Determine most of a membranes functions. Classified structurally as integral proteins or peripheral proteins.
Structure of integral proteins
Embedded within and extend across lipid bilayer. Make good channel proteins for transportation of substances into an out of the cell
Structure of peripheral proteins
Are not embedded in lipid bilayer.
Function of transport proteins
Regulate movement of substances across cell membrane. Can be channel proteins, carrier proteins, pumps, symporters, and antiporters.
Function of cell surface receptor
Bind ligand molecules, such as neurotransmitters and hormones, released from a specific cell.
Function of identity markers
Communicate to other cells that they belong to the body. Immune system cells distinguishing healthy cells from foreign cells.
Function of enzymes
Catalyze chemical reactions
Function of anchoring sites
Secure cytoskeleton to plasma membrane
Function of cell-adhesion proteins
Perform cell to cell attachements
Two categories of membrane transport
Passive or active transport
Characteristics of passive transport
Do not require energy Depend on substances moving down with "[ ]" gradient Includes two types: Diffusion (several types) Osmosis
Define diffusion
The movement of a dissolved substance (solute) from an area of greater concentration of that dissolved substance to are of lesser concentration of that dissolved substance.
Two conditions that affect the rate of diffusion
Steepness and temperature
Two types of diffusion
Simple and facilitated diffusion
Define Simple Diffusion
Solutes that are small and nonpolar move down their concentration gradient passing between the phospholipid molecules. Movement is dependent on concentration gradient alone.
Define facilitated diffusion
A transport process for small, charged and small, polar solutes. Requires assistance from plasma membrane proteins. Two subtypes:
Channel mediated
Carrier mediated
More transport proteins, faster diffusion
Function of channel mediated diffusion
Movement of small ions through water-filled protein channels. Specific to one ion type. Involves either leak channels which are continuously open or gated channels which are usually closed (open to response of stimuli).
No energy required
Function of carrier mediated diffusion
Small, polar molecules are assisted across the membrane by carrier proteins. Binding of a substance causes a change in the carrier protein shape. Substances are then released on other side of the cell membrane. Uniporter
Define osmosis
Passive movement of water through a selectively permeable membrane from an are of low concentration of nonpenetrating solute particles to an area of high concentration of nonpenetrating solute particles.
Two types of solutes
Penetrating ad nonpenetrating
Define penetrating solutes
Pass through phospholipid bilayer
Small and nonpolar
Define nonpenetrating solutes
Prevented from passing through bilayer
charged, polar, or large
Define aquaporins
An integral protein water channel
Define osmotic pressure
The pressure exerted by the movement of water across a semi-permeable membrane due to a difference in solution concentration
Define tonicity
Ability of a solution to change the volume of the cell by osmosis