Chapter 4- Microbiology Flashcards
Microbiology
Study of microorganisms.
Contamination
Soiled by contact with infections organisms or other material
Bacterial cells
Have no membrane to separate nucleus ( one strand of DNA) from cytoplasm
95% are beneficial and essential
Pathogens
Microorganisms that cause illness produce powerful toxins that entire with body systems.
Capable of causing disease
Microns
How to measure bacteria. 1/1000 of a ml
Aerobic
Need oxygen
Anaerobic
Can live with out oxygen
Shape
Spherical-circle or sphere (cocci)
Rod- bacillus
Spiral- spirilla
Endosperm
Micro. Able to form thick wall around self to be able to survive in adverse conditions ‘ resistant bacterium
What conditions micro. Need to grow and reproduce
PH, oxygen requirements,temperature, nutritional needs, light moisture / humidity
Psychrophile
Likes cold (59-68)
Mesophiles
Most pathogenic to humans
Like 68-113
thermophiles
Like heat ( 122-158)
PH of pathogen
7-7.8 ( same as blood)
Vegetative stage
State of active growth
Angstrom
Unit used to measure length of light waves
Binary fission
Bacterial division → 2 equal parts, every 20min.
MRSA (methicillin-resistant staphylococcus aureus)
Lives on skin
Vancomycin - resistant enterococci (vre)
Lives in bowels
Vancomycin-resistant streptococcus pneumoniae
Lives asymptotically in nose and pharynx
Klebsiella
On hands an gi tract
A cinetobacter
Found in soil
Carbapenem-resistant enterobacteriaceae
High antibiotic resistance, normal part of human gut
→ become carbapenem resistant→associated with endoscopes, ventilators, urinary catheters, iv CATHS
Pseudomonas aeruginosa
Water-bug. Occur with severe burns patients with aids, immunocompromised.
Blood borne pathogens
HIV HBV, HCV most prevalent chronic
Protozoa
One-celled animal organism.
Trophozoite= feeding stage
Fungi
Molds, mushroom, yeast
Plant-like
Prions
Pathogenic agent transmissible and able to induce abnormal folding of specific normal cell proteins (found usually in the brain) -
TSE = transmissible spongiform encephalopathies → long incubation period neuronal loss t failure to induce inflame. Response.
Resistant to heat and disinfect, agents
Example of a TSE
CJD = creutzfeldt -jakob disease
30yr incubation
Prions found in brain, duramater and eyes
Seldom in blood urine skin bone nerves feces saliva, eye.