Chapter 4 - Basic Principles of Pharmacology Flashcards
drug enforcement administration
promote and protect the public health by helping safe and effective products reach the market in a timely way and monitoring products for continued safety after they are in use
bioequivalence
quality of having the same drug strength and providing an equivalent amount of drug to the target tissue in the same dosage as another sample of a given drug substance
Schedule I
no accepted medical used in US/high abuse potential
- opium/LSD
Schedule II
high abuse potential/severe psychic or physical dependence liability
- morphine, cocaine
Schedule III
drugs with less abuse potential
- stimulants/depressants
- narcotics
Schedule IV
less abuse potential than schedule II
- barbital
Schedule V
less abuse potential than IV
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Administration
direct application of a single dose of a drug
dispensing
act of delivering a medication to an ultimate user pursuant to a medical order issued by a practitioner authorized to prescribe
administration and dispensing
require a prescription
Absorption
process of getting the drug into the body through a variety of routes, including oral, rectal, vaginal, intravenous, intramuscular, inhalation, and topical application
Distribution
the process of moving the drug throughout the body
Metabolism
complex process by which a drug is changed into one or more chemical entities that differ from the parent drug
- occurs in the liver
Elimination
process of getting a drug out of the body
Clearance
the measure of the body’s ability to eliminate a drug
- the volume of blood that is cleared of a drug over a given period of time
