Chapter 4 Flashcards
Glass lenses magnify the image of the specimen in
Light microscopy
Electrons are passed through a thin specimen for viewing on a screen in
Transmission electron microscopy (TEM)
Electrons are reflected off the surface of the specimen for viewing on a screen in
Scanning electron microscopy (SEM)
The average size of a human cell is
30um
Human cells range from the smaller _______ to the largest ________
Red blood cell at 7-8 um, oocyte at 120um
Human cells can have a variety of shapes such as
Cube, round, columnar, cylinder, disc or irregular
The shape and size of a human cell determines its
function
The three main structural components of a cell are
Plasma (cell) membrane, nucleus, cytoplasm
Membrane bound organelles include:
Rough ER, smooth ER, mitochondria, Golgi apparatus, peroxisome and lysosome
Non-membrane bound organelles include:
Ribosomes, centrosome, proteasome and cytoskeleton
Cell organelles are permanent features while stored molecules named ______ vary in amount and presence
Inclusions
Three primary functions of any cell are:
Maintain integrity and shape, get nutrients for metabolism, dispose of wastes
The lipid components in a cell membrane include
Phospholipids, cholesterol and glycolipids
The cell membrane lipids that form a barrier between the cytoplasm and interstitial fluid are:
Phospholipids
The cell membrane lipids that strengthens and stabilizes the membrane is
Cholesterol
The cell membrane lipids that contribute to the glycocalyx are
Glycolipids
In a membrane’s bilayer, this region is hydrophobic (water-repelling).
fatty acid tails in the middle of the membrane
Cell membrane proteins that extend across the width of the membrane are _____ while those associated with only one of the cell membrane surfaces are ____
Integral, peripheral
The six major roles of membrane proteins are:
Transport, receptor, identity marker, enzyme, anchoring site, cell-adhesion
These membrane proteins have binding sites for chemical messengers (ligands).
receptors
These membrane proteins break down chemicals, such as chemical messengers that have finished stimulating the cell.
enzymes
These membrane proteins regulate movement of substances across the membrane, and include channels, carriers, and pumps
transport proteins
Ions and water can enter or leave the cell through this type of protein in the plasma membrane.
gated or leak channels
These transport proteins allow small molecules (such as water) and ions (such as sodium) to continually pass in and/or out of a cell.
leak channels
These transport proteins can open and close to control the movement of ions into and/or out of a cell.
gated channels
. These glycoproteins contribute to the glycocalyx and help the immune system recognize normal body cells.
Identity marker molecules
. These membrane proteins attach to similar proteins in neighboring cells, to hold cells together, and to extracellular molecules, allowing communication with other cells.
Cell-adhesion proteins
These membrane proteins or glycoproteins bind to specific chemicals which can signal the cell to perform a specific activity
receptor proteins
These membrane proteins attach to cytoskeletal proteins
Anchoring proteins
The movement of a substance from an area of high concentration to an area of low concentration, powered by the kinetic energy of the individual particles.
diffusion
What is the effect of all of the following on the diffusion rate?
1. higher temperature 2. lower molecular weight 3. steeper concentration gradient 4. greater surface area 5. higher permeability
increase diffusion rate
The movement of small, nonpolar molecules down a concentration gradient existing across a cell membrane is an example of
Simple diffusion
Oxygen, carbon dioxide, and steroids can enter or leave a cell through this part of the plasma membrane.
lipid bilayer
The movement of charged, polar molecules down a concentration gradient existing across a cell membrane requires a channel protein; this process is
Facilitated diffusion
The diffusion of water through a selectively permeable membrane; the result is a change in the volume of fluid on both sides of the membrane.
osmosis
This is a measure of the hydrostatic pressure required to stop osmosis.
osmotic pressure
Name the two processes that move a substance against its concentration gradient
Active transport and secondary active transport (coupled transport)
This process uses energy derived directly from ATP breakdown to move a substance against its concentration gradient
Active transport
This process uses energy derived from the movement of second substance moving down its concentration gradient to move a substance against its concentration gradient
Secondary active transport (coupled transport)
General term for vesicular transport mechanisms that bring large particles or objects into a cell.
endocytosis
Vesicular transport used to excrete substances from a cell.
exocytosis
Engulfment of large particles -even whole cells - by specialized cells such as white blood cells.
phagocytosis
Nonspecific intake of proteins by most cells is by this vesicular transport process.
pinocytosis
Selective intake of specific substance by vesicular transport
receptor-mediated endocytosis