Chapter 4

Question 1

Function to ensure compliance wuith the controlled substances act of 1970.

Answer 1

DEA

Question 2

Mission is to promote and protect the public health by helping safe and effective products reach the market in a timely way and monitoring products for continued safety after they are in use.

Answer 2

FDA

Question 3

Bioequivalence

Answer 3

Comparable drugs must…

Have the same dosage form (tablet, suspension)

Have the same drug strength

Provide equivalent blood levels or tissue levels of the drug.

Question 4

Administration

Answer 4

Is the direct application of a single does of a drug.

(what athletic trainers do)

Question 5

Dispensing

Answer 5

Is the act of delivering a medication to an ultimate user pursuant to a medical order issued by a practiioner authorized to prescribe.

Question 6

Pharmacology

Answer 6

Study of drugs and includes pharmacokinetics and pharmacodynamics.

Question 7

Pharmacodynamics

Answer 7

Describes the actions of a drug on the body, including its mechanism of action and medicinal effect. (the biochemical and physiological effects of the drug)

mechanism of action, drug interactions, side effects, adverse reactions, and allergic reactions.

Question 8

Pharmacokinetics

Answer 8

Describes how the body acts on the drug. Pharmacokinetics includes absorption, distribution, metabolism, and elimination of the drug in the body.

Question 9

Absorbtion

Answer 9

Process of getting a drug into the body.

Can be absorbed through many ways including rectal, intestinal, and dermal tissue.

Question 10

Distribution

Answer 10

Refers to the process of moving the drug throughout the body.

Question 11

Low Vs. High Volume of distribution

Answer 11

Low - Higher plasma concentrations and less distribution into extravascular spaces

High - Lower plasma concentrations and more distribution into extravascular spaces

Question 12

Metabolism

Answer 12

Complex process by which a drug is changed into one or more chemical entities that differ from the parent drug.

Question 13

Elimination

Answer 13

The process of getting a drug out of the body.

Question 14

Clearance

Answer 14

Measure of the body’s ability to eliminate a drug. it describes the volume of blood that is cleared of the drug over a period of time.

Question 15

Half-life

Answer 15

Length of time that it takes for blood levels or tissue levels of a drug to decrease by one half.

Question 16

Dissolution

Answer 16

is the process of dissolving a substance. Process of solid or oral medications being dissolved in the GI tract so that it can be absorbed.

Question 17

Routes of drug Administration

Answer 17

Oral

Intravenous

Intramuscular

Subcutaneous

Inhalation

Intraarterial

Sublingual

Rectal

Topical

Question 18

Agonists

Answer 18

Drugs that exert their effect by attaching to cellular receptors in the body. The cause STIMULATION of the receptor ( acting as endogenous chemicals)

ex. Morphine

Question 19

Antagonists

Answer 19

Act by binding to cellular receptors, but they dont cause stimulation of the receptor they bloke the receptor from being stimulated.

Example: Anti-histamine

Question 20

What % of high school athletes admitt to taking NSAIDs without supervision

Answer 20

75%

Question 21

Inflammation

Answer 21

RED

PAIN

SWELLING
HEAT
LOSS OF FUNCTION

Question 22

Process of Inflammation

Answer 22

1. Vasodialation and increased blood flow to the area.
2. escape of plasma fluid and protiens into the interstitial space
3. Neutrophil emigration and accumulation at the site of injury and the release of chemical mediators, which result in fluid escaping from the cells into the interstitial space