Chapter 38 Carcinoma of the Ovary and Fallopian Tube

Question 1

risk reducing salpingo-oophrectomy associated with statistically significant reduction in both

Answer 1

breast and ovarian/fallopian tube cancer in BRCA1 or BRCA2 mutation carriers

Question 2

positive predictive value for routine screening for ovarian cancer was _ for an abnormal ca-125, 1% for abnormal tvs and _ if both tests were abnormal

Answer 2

3.7% for abnormal ca125
1% for abnormal TVUS
23.5% if both tests were abnormal

Question 3

immediate treatment of recurrence based on ca-125 elevation (Doubling from baseline) alone may have similar overall survival with that of delayed treatment arm (await clinical symptoms)

Answer 3

true

Question 4

ovarian cancer is 2nd most common gynecologic malignancy following uterine cancer

Answer 4

true

Question 5

5th leading cause of deaths in females in the US.

Answer 5

true.

Question 6

lifetime risk of ovarian cancer

Answer 6

1:70

Question 7

peak incidence in _ and _

Answer 7

60s and 70s

Question 8

overall 5 year survival rate is

Answer 8

46%

Question 9

risk factors for ovarian cancer:

Answer 9

nulliparous, early menarche, late menopause, infertility