Chapter 38 39 40 24 25. 26 And 27 Flashcards
What is the area of the kidneys that contains the glomeruli and portions of the tubules called?
a. Medulla
b. Cortex *****
c. Pyramids
d. Columns
What is the functional unit of the kidney called?
a. Glomerulus
b. Nephron *****
c. Collecting duct
d. Pyramid
What is the only surface inside the nephron where cells are covered with microvilli to increase the reabsorptive surface area called?
a. Proximal convoluted tubules ***
b. Distal tubules
c. Ascending loop of Henle
d. Descending loop of Henle
What part of the kidney controls renal blood flow, glomerular filtration, and renin secretion?
a. Macula densa
b. Visceral epithelium
c. Juxtaglomerular apparatus (JGA) ****
d. Filtration slits
Innervation of the bladder and internal urethral sphincter is supplied by which nerves?
a. Peripheral nerves
b. Parasympathetic fibers ****
c. Sympathetic nervous system
d. Tenth thoracic nerve roots
How much urine accumulates in the bladder before the mechanoreceptors sense bladder fullness?
a. 75 to 100 mL
b. 100 to 150 mL
c. 250 to 300 mL ***
d. 350 to 400 mL
What is the trigone?
a. A smooth muscle that comprises the orifice of the ureter
b. The inner mucosal lining of the kidneys
c. A smooth triangular area between the openings of the two ureters and the urethra *****
d. One of the three divisions of the loop of Henle
The glomerular filtration rate is directly related to which factor?
a. Perfusion pressure in the glomerular capillaries ****
b. Diffusion rate in the renal cortex
c. Diffusion rate in the renal medulla
d. Glomerular active transport
On average, what percent of cardiac output do the kidneys receive?
a. 10% to 20%
b. 15% to 20%
c. 20% to 25% *****
d. 30% to 35%
What are blood vessels of the kidneys innervated by?
a. Vagus nerve
b. Sympathetic nervous system **
c. Somatic nervous system
d. Parasympathetic nervous system
When renin is released, it is capable of which action?
a. Inactivation of autoregulation
b. Direct activation of angiotensin II
c. Direct release of antidiuretic hormone (ADH)
d. Formation of angiotensin I **
A student asks the professor to explain what effect natriuretic peptides have during heart failure when the heart dilates. Which response by the professor is best?
a. Stimulates antidiuretic hormones
b. Inhibits antidiuretic hormones
c. Stimulates renin and aldosterone
d. Inhibits renin and aldosterone****
What is the direct action of atrial natriuretic hormone?
a. Sodium retention
b. Sodium excretion **
c. Water retention
d. Water excretion
What term is used to identify the movement of fluids and solutes from the tubular lumen to the peritubular capillary plasma?
a. Tubular secretion
b. Ultrafiltration
c. Tubular reabsorption ****
d. Tubular excretion
A patient’s urinalysis came back positive for glucose. What does the healthcare professional expect the patient’s blood glucose to be at a minimum?
a. 126 mg/dL
b. 150 mg/dL
c. 180 mg/dL **
d. 200 mg/dL
Which hormone is required for water to be reabsorbed in the distal tubule and collecting duct?
a. Antidiuretic hormone ***
b. Aldosterone
c. Cortisol
d. Adrenocorticotropic hormone
Which glycoprotein protects against urolithiasis?
a. Uromodulin ***
b. Nephrin
c. Urodilatin
d. Cystatin
What is the end product of protein metabolism that is excreted in urine?
a. Glucose
b. Ketones
c. Bile
d. Urea ****
What is the action of urodilatin?
a. Urodilatin causes vasoconstriction of afferent arterioles.
b. It causes vasodilation of the efferent arterioles.
c. Urodilatin inhibits antidiuretic hormone secretion.
d. It inhibits salt and water reabsorption.*****
The concentration of the final urine is determined by antidiuretic hormone (ADH), which is secreted by which gland?
a. Posterior pituitary ***
b. Thyroid
c. Parathyroid
d. Anterior pituitary
What does the healthcare professional understand about urodilatin?
a. Urodilatin inhibits sodium chloride and water reabsorption in the medullary part of the collecting duct.
Hey
b. It inhibits antidiuretic hormone (ADH) to prevent water reabsorption in the medullary part of the collecting duct.
c. Urodilatin is stimulated by a rise in blood pressure and an increase in extracellular volume. *******
d. It is stimulated by a fall in blood pressure and a decrease in extracellular volume
What substance stimulates renal hydroxylation in the process of producing vitamin D?
a. Erythropoietin
b. Thyroid hormone
c. Calcitonin
d. Parathyroid hormone*****
Which hormone is synthesized and secreted by the kidneys?
a. Antidiuretic hormone
b. Aldosterone
c. Erythropoietin****
d. Angiotensinogen
The student wants information about a patient’s renal function. What test does the healthcare professional tell the student to evaluate?
a. Glomerular filtration rate **
b. Hourly urine output
c. Serum blood urea nitrogen and creatinine
d. The specific gravity of the solute concentration of the urine
Which renal change is found in older adults?
a. Sharp decline in glomerular filtration rate
b. Sharp decline in renal blood flow
c. Decrease in the number of nephrons ***
d. Decrease in urine output
A healthcare professional is caring for an older adult. Understanding age-related renal changes, what urinalysis finding would the professional view as normal for an older patient?
a. pH 5.2
b. Moderate protein
c. Specific gravity 1.003****
d. Positive for white cell casts
What process allows the kidney to respond to an increase in workload?
a. Glomerular filtration
b. Secretion of 1,25-dihydroxyvitamin D3
c. Increased heart rate
d. Compensatory hypertrophy *****
Which process makes it possible for ureters to be transplanted successfully?
a. Compensatory hypertrophy
b. Erythropoietin secretion
c. Peristalsis *******
d. Collateral circulation
How does progressive nephron injury affect angiotensin II activity?
a. Angiotensin II activity is decreased.
b. Angiotensin II activity is elevated. ****
c. Angiotensin II activity is totally suppressed.
d. Angiotensin II activity is not affected.
A patient has been diagnosed with a renal stone. Based on knowledge of common stone types, what self-care measure does the healthcare professional plan to teach the patient when stone analysis has returned?
a. Increase water intake.
b. Decrease soda intake.
c. Restrict animal protein in the diet.
d. Ingest 1000 mg of calcium a day.*******
The student asks the professor to explain the role of pyrophosphate, potassium citrate, and magnesium in the formation of kidney stones. What response by the professor is best?
a. They inhibit crystal growth. ***
b. They stimulate the supersaturation of salt.
c. They facilitate the precipitation of salts.
d. They enhance crystallization of salt crystals
Hypercalciuria is primarily attributable to which alteration?
a. Defective renal calcium reabsorption
b. Intestinal hyperabsorption of dietary calcium **
c. Bone demineralization caused by prolonged immobilization
d. Hyperparathyroidism
Detrusor hyperreflexia develops from neurologic disorders that originate where?
a. Spinal cord between C2 and C4
b. Spinal cord between S2 and S4
c. Above the pontine micturition center **
d. Below the cauda equina
A patient has overactive bladder syndrome. Which classification of drug does the healthcare professional plan to teach the patient about?
a. B-Adrenergic blocking medications
b. a-Adrenergic blocking medications ***
c. Parasympathomimetic medications
d. Anticholinesterase medications
Bladder cancer is associated with the gene mutation of which gene?
a. c-erbB2
b. Human epidermal growth factor receptor 2 (HER2)
c. TP53 *******
d. myc
A female patient has been diagnosed with an uncomplicated urinary tract infection. What self care measure does the healthcare provider teach the patient that is specific to this type of infection?
a. Drink at least eight glasses of water a day.
b. Take medication if you have a fever.
c. Rest as much as you can in the next few days.
d. After using the bathroom, wipe from front to back.****
A healthcare professional is assessing a patient who could have either pyelonephritis or cystitis. Which differentiating sign would assist the professional in making this diagnosis?
a. Difficulty starting the stream of urine
b. Spasmodic pain that radiates to the groin
c. Increased glomerular filtration rate
d. Urinalysis confirmation of white blood cell casts ***
An 85-year-old person has a urinary tract infection. What clinical manifestation does the healthcare professional expect to see in this person?
a. Confusion and poorly localized abdominal discomfort ***
b. Dysuria, frequency, and suprapubic pain
c. Hematuria and flank pain
d. Pyuria, urgency, and frequency
Pyelonephritis is usually caused by which type of organism?
a. Bacteria ***
b. Fungi
c. Viruses
d. Parasites
Which abnormal laboratory value is found in glomerular disorders?
a. Elevated creatinine concentration***
b. Low blood urea nitrogen (BUN)
c. Elevated immunoglobulin A (IgA)
d. Low serum complement
Which glomerular lesion is characterized by thickening of the glomerular capillary wall with immune deposition of immunoglobulin G (IgG) and C3?
a. Proliferative
b. Membranous **
c. Mesangial
d. Crescentic
Goodpasture syndrome is an example of which of these?
a. Antiglomerular basement membrane disease **
b. Acute glomerulonephritis
c. Chronic glomerulonephritis
d. Immunoglobulin A (IgA) nephropathy
A patient exhibits symptoms including hematuria with red blood cell casts and proteinuria exceeding 3 to 5 g/day, with albumin as the major protein. What diagnostic test or treatment regime does the healthcare professional educate the patient on?
a. Intravenous pyelogram
b. Oral antibiotics
c. Renal biopsy **
d. Cyclophosphamide
Hypothyroidism, edema, hyperlipidemia, and lipiduria characterize which kidney disorder?
a. Nephrotic syndrome *******
b. Acute glomerulonephritis
c. Chronic glomerulonephritis
d. Pyelonephritis
A patient who has a history of mildly decreased renal function is admitted to the hospital for IV antibiotics. Which antibiotics would the healthcare professional avoid in this patient?
a. Penicillin and ampicillin
b. Vancomycin and bacitracin
c. Gentamicin and tobramycin *****
d. Cefazolin and cefepime
Which urine characteristics are indicative of acute tubular necrosis (ATN) caused by intrinsic (intrarenal) failure?
a. Urine sodium >30 mEq/L ****
b. Urine osmolality >500 mOsm
c. Fractional excretion of sodium (FENa) <1%
d. Urine sediment has no cells, some hyaline casts
How are glucose and insulin used to treat hyperkalemia associated with acute renal failure?
a. Glucose has an osmotic effect, which attracts water and sodium, resulting in more dilute blood and a lower potassium concentration.
b. When insulin transports glucose into the cell, it also carries potassium with it.**
c. Potassium attaches to receptors on the cell membrane of glucose and is carried into the cell.
d. Increasing insulin causes ketoacidosis, which causes potassium to move into the cell in exchange for hydrogen.
Creatinine is primarily excreted by glomerular filtration after being constantly released from what type of tissue?
a. Nervous system
b. Kidneys
c. Muscle **
d. Liver
A professor has taught a student about skeletal alterations seen in chronic kidney disease. Which statement by the student indicates the professor needs to give more information?
a. Parathyroid hormone is no longer effective in maintaining serum phosphate levels.
b. The parathyroid gland is no longer able to secrete sufficient parathyroid hormone. *****
c. The synthesis of 1,25-vitamin D3, which reduces intestinal absorption of calcium, is impaired.
d. The effectiveness of calcium and phosphate resorption from bone is impaired.
A patient who has chronic kidney disease has hemoglobin of 7.2 mg/dL. What treatment does the healthcare professional prepare the patient for?
a. Intrinsic factor
b. Vitamin B12
c. Vitamin D
d. Erythropoietin ***
When the right kidney is obstructed, how will the glomeruli and tubules in the left kidney compensate?
a. Increase in number
b. Increase in size ****
c. Develop collateral circulation
d. Increase speed of production
What medical term is used to identify a functional urinary tract obstruction caused by an interruption of the nerve supply to the bladder?
a. Neurogenic bladder **
b. Obstructed bladder
c. Necrotic bladder
d. Retrograde bladder
The functional kidney is associated with which embryonic organ?
a. Metanephros**
b. Mesonephros
c. Pronephros
d. Endonephros
When does urine formation and excretion begin?
a. At birth
b. By 3 months’ gestation ***
c. By 6 months’ gestation
d. By 8 months’ gestation
Compared with an adult, an infant has a greater content of extracellular fluid, as well as a greater rate of fluid exchange. What effect does this have on the fluid balance of a child compared with that of an adult?
a. Edema development is less of a problem.
b. Overhydration is not difficult to manage.
c. Daily fluid requirements are greater.
d. The control of dehydration is more difficult.****
What term is used to identify the condition that exists when the urethral meatus is located on the undersurface of the penis?
a. Hypospadias ****
b. Epispadias
c. Hyperspadias
d. Chordee
What initiates inflammation in acute poststreptococcal glomerulonephritis?
a. Lysosomal enzymes
b. Endotoxins from Streptococcus
c. Immune complexes *******
d. Immunoglobulin E (IgE)–mediated response
Acute glomerulonephritis (AGN) may be accompanied by a positive throat or skin culture for which bacteria?
a. Staphylococcus aureus
b. Streptococcus ****
c. Pseudomonas aeruginosa
d. Haemophilus
A child with acute poststreptococcal glomerulonephritis is voiding smoky, brown-colored urine and asks the healthcare professional to explain what causes it. What explanation by the professional is best?
a. Presence of red blood cells ***
b. Presence of urobilinogen
c. Slough from the collecting tubules
d. Protein in the urine
In immunoglobulin G (IgG) nephropathies such as glomerulonephritis, IgG is deposited in which location?
a. Juxtamedullary nephrons
b. Glomerulus basement membranes *******
c. Mesangium of the glomerular capillaries
d. Parietal epithelium
What is the pathophysiologic process responsible for the autoimmune disorder of hemolyticuremic syndrome (HUS)?
a. Immunoglobulin A (IgA) coats erythrocytes that are destroyed by the spleen, and remnants are excreted through the kidneys.
b. Verotoxin from Escherichia coli is absorbed from the intestines and damages erythrocytes and endothelial cells. ****
c. Endotoxins from E. coli block the erythropoietin produced by the kidneys, which reduces the number of erythrocytes produced by the bone marrow.
d. Failure of the nephron to filter urea increases the blood urea nitrogen, which binds to erythrocytes that are subsequently destroyed by the spleen.
What is the first indication of nephrotic syndrome in children?
a. Periorbital edema *******
b. Scrotal or labial edema
c. Frothy urine
d. Ascites
Bacteria gain access to the female urinary tract by which means?
a. Systemic blood that is filtered through the kidney
b. Bacteria traveling from the lymph adjacent to the bladder and kidneys
c. Bacteria ascending the urethra into the bladder**
d. Colonization of the bladder when urine is static