Chapter 30: Transfusion

Question 1

True or False? Anti- A and Anti- B antibodies are warm antibodies.

Answer 1

FALSE!! They are cold antibodies because they are usually IgM
“ remember it is Cold in the Mountains ( m for igM and m for Mountains where it is cold)”

Question 1

What is the usual antibody associated with ABO grouping?

Answer 1

IgM

Question 2

True or False? Only IgG antibodies are capable of transplacental passage from mother to fetus and the most important immune antibody is the Rh antibody, anti-D.

Answer 2

TRUE!!

Question 3

What is the proteins that defines the ABO antigens?

Answer 3

Glycosyltransferase that is encoded from a single gene for which there are three major alleles, A, B and O.

Question 4

What are the naturally occurring antibodies in Group O blood group?

Answer 4

Anti-A, anti-B

Question 5

What are the naturally occurring antibodies in Group A blood group?

Answer 5

Anti-B

Question 6

What are the naturally occurring antibodies in Group B blood group?

Answer 6

Anti-A

Question 7

True or False? There are NO naturally occurring antibodies in Group AB?

Answer 7

TRUE!!

Question 8

True or False? Rh antibodies rarely occur naturally and are therefore immune antibodies that result from previous transfusion or pregnancy.

Answer 8

TRUE!!

Question 9

Fill in the blanks. “ ______________ is important in detecting IgM antibodies, usually at room temperature or at 4°C (e.g. anti-A, anti-B).”

Answer 9

Saline agglutination