Chapter 3 - Factors Affecting Wound Healing

Question 1

4 Main Factors for wound healing

Answer 1

1. wound characteristics
2. local factors
3. systemic factors
4. inappropriate wound management

Question 2

Characteristics that affect rate of wound healing

Answer 2

Mechanism of onset
Time since onset
Wound location
Wound dimension
Temperature
Wound hydration
Infection
Necrotic tissue/foriegn bodies

Question 3

Rank wounds in terms of healing time: square, linear, circular

Answer 3

Linear, square, circular

Question 4

What’s the ideal temperature?

Answer 4

98.6 - 100.4 degrees

Question 5

Clinical word for dry wound

Answer 5

Dessication

Question 6

Clinical word for wet wound

Answer 6

Maceration

Question 7

What is normal skin microflora?

Answer 7

up to 10^3 per g/tissue.

Staphylococcus
Microboccus
Petptococcus
Streptococcus
Acinetobacter
Yeast

Question 8

Chronic wounds have increases in _____ cells and decreases in ____ cells.

Answer 8

Increase = inflammatory mediators, tumor necrosis, MMPs

Decrease = TIMPs

Imbalance leads to breakdown of ECM and inhibits granular tissue formation

Question 9

What are the local factors?

Answer 9

Circulation
Sensation
Mechanical stress

Question 10

What are the systemic factors?

Answer 10

Age
Inadequate nutrition
Comorbidities
Medication
Behavioral risk taking

Question 11

What are the effects of steroids on wound healing?

Answer 11

Suppress inflammation and immune system, decrease angiogenesis and epithelialization, and slow cell proliferation. Decrease collagen synthesis, wound contraction, wound tensile strength.

Question 12

NSAIDS

Answer 12

decrease in wound tensile strength, regular use results in delayed and abnormal bone healing