Chapter 2 - Phases of Healing

Question 1

Cytokines

Answer 1

signal proteins

Question 2

Growth factors

Answer 2

cell growth and differentiation

Question 3

Chemotactic agents

Answer 3

attract cells for wound repair

Question 4

What occurs during the second vascular response?

Answer 4

vasodilation. exudate formation, histamine release (short term) and prostaglandin (long term)

Question 5

Cardinal Signs of Inflammation

Answer 5

Swelling
Redness
Warmth
Pain
Decreased function

Question 6

What do PMNs do?

Answer 6

first WBC to reach injury. stimulate fibroblast migration. clean wound by scavenging.

Question 7

What occurs during maturation and remodeling?

Answer 7

new collagen synthesis
old collagen broken down by collagenases
reorientation of collagen fibers
may occur up to 2 years

Question 8

What are the 4 phases of proliferation?

Answer 8

Angiogenesis
Granulation tissue formation
Wound contraction
Epithelialization