Chapter 2 - Phases of Healing Flashcards
1
Q
Cytokines
A
signal proteins
2
Q
Growth factors
A
cell growth and differentiation
3
Q
Chemotactic agents
A
attract cells for wound repair
4
Q
What occurs during the second vascular response?
A
vasodilation. exudate formation, histamine release (short term) and prostaglandin (long term)
5
Q
Cardinal Signs of Inflammation
A
Swelling Redness Warmth Pain Decreased function
6
Q
What do PMNs do?
A
first WBC to reach injury. stimulate fibroblast migration. clean wound by scavenging.
7
Q
What occurs during maturation and remodeling?
A
new collagen synthesis
old collagen broken down by collagenases
reorientation of collagen fibers
may occur up to 2 years
8
Q
What are the 4 phases of proliferation?
A
Angiogenesis
Granulation tissue formation
Wound contraction
Epithelialization
