Chapter 3: Biological Foundations Flashcards

You may prefer our related Brainscape-certified flashcards:
1
Q

Genotype

A

Inherited genetic material

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Phenotype

A

Expression of genes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Environment

A

Defined as everything outside of your genetics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

The human genome

A

Made up of ~20,000 protein coding genes (smaller than estimates); most genes are shared among all living things; genes make up only 1% of the human genome (the rest is non-coding DNA)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Five interactions that build a human

A

Parent and child genotype; child genotype on parent phenotype; child’s environment and child’s phenotype (two-way interaction); child’s environment on child’s genotype

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Parent Genotype affect on Child genotype

A

Transmission of genetic material from parent to offspring (chromosomes, DNA, genes). Affect development and behavior through protein manufacturing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Mutations

A

Change in DNA caused by random error or environmental factors; fatal more often than not

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Crossing over

A

Sections of DNA switch chromosomes in gametes. Occurs prior to conception in the sex cells. Two members of a chromosome pair swap DNA sections

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Regulator genes

A

Switch on and off genes; control diversity in genetic expression

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Sex Chromosomes

A

X and Y; XX = female, XY = male, any other combination = intersex.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Sex linked disorders

A

Genetic mutations that occur only on the X chromosome. More likely to present in males because there is only one copy of the X gene, and no healthy X to replace that mutated data

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Alleles

A

Different forms of genes. Dominant and recessive; homozygous (2 same alleles) and heterozygous (2 different alleles)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Child’s genotype affect on child’s phenotype

A

Genes affect physical and behavioral characteristics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Endophenotypes

A

Intermediate phenotypes that mediate pathways between genes and behaviors. Do not involve overt behavior

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Polygenic inheritance pattern

A

many different genes determine the phenotype

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

PKU example

A

Example of the genotype affecting the phenotype. If a child is born with PKU and they eat reactive foods they are likely to have issues, but if they avoid the foods then the genetic issue does not present

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Child’s Environment affect on child’s phenotype

A

pre and post natal environments can change how genes are expressed; prenatal tests can screen baby and parents for possibly genetic defects that can be treated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Norm of reaction

A

All possible gene expressions given a certain environment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Child’s phenotype affect on Child’s environment

A

The child’s gene expression and behaviors causes their environment to adapt to their needs. Children are active creators of their environment (select surroundings that match their interests/personalities)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Child’s Environment affect on Child’s genotype

A

Epigenetic mechanisms can alter gene functions despite DNA being “fixed”; can occur before or after gestation

21
Q

Histone modification

A

Proteins affected by DNA strand that change expression

22
Q

Methylation

A

Silencing of gene expression by blocking transcription in the promoter region of a gene (modified by stress)

23
Q

Behavioral genetics

A

Science concerned with how environment and genes influence behavior and development

24
Q

Heritability

A

Statistical estimate of how much of a measured variance on a phenotypic trait is attributable to genetic difference; not immutability; not generalizable (can change based on culture and environmental factors)

25
Q

Multifactoral traits

A

Traits that are affected by environmental and genetic factors

26
Q

Genome-wide association studies (GWAS)

A

Link specific DNA segments with specific traits

27
Q

Genome-wide complex trait analysis (GCTA)

A

takes estimates of genetic resemblance across large groups of individuals

28
Q

Experience-expectant plactisity

A

the role of general human (species-specific) experience in shaping development. The species has evolved to expect reliable post-natal stimuli to facilitate development

29
Q

Experience-dependent plasticity

A

Neural connections are created and reorganized as a result of individual life experiences. Cortical areas can grow for specific training of specific body parts/behaviors

30
Q

Sensitive periods

A

Timing where an experience-expectant process is the most sensitive to input/changeF

31
Q

Frog cell plasticity example

A

A cell from the belly of a frog can be moved to the mouth area, and will become a mouth cell. Moving the same belly frog cell to the mouth of a salamander will still produce a frog mouth cell. The species does not matter, but the cell can still differentiate depending on location

32
Q

Cerebral cortex

A

Grey matter that takes up 80% of the brain and is responsible for higher function. Separated into four lobes

33
Q

Hippocampus

A

Involved in memory and learning

34
Q

Amygdala

A

Involved in arousal and four Fs (fight flight feed fuck)

35
Q

Basal ganglia

A

Involved in voluntary movements, decision making, learning and memory

36
Q

Neurons

A

Cells that carry electric potential and can communicate with each other; more than 100 billion in the brain

37
Q

Pyramidal cells

A

Triangle shape, very long, transmit info between regions

38
Q

Marian Diamond

A

Very famous neuroscientist

39
Q

Glial cells

A

Support cells that assist functions in the axon/neuron; creates myelin sheaths, cleans the synaptic space, and can lead to increased IQ

40
Q

Synaptic pruning

A

The brain gets rid of neurons over development, and cortical mass decreases. (mass loss occurs in the cortex and basal ganglia, but mass gain occurs in the hippocampus)

41
Q

Neurogenesis

A

Proliferation of neurons through cell division

42
Q

Spines

A

Formations on dendrites that increase connection capacity

43
Q

Plasticity

A

Capacity of the brain to be changed by experience (decreased by myelination)

44
Q

Synaptogenesis

A

Process where neurons form synapses with other neurons

45
Q

Synapse elimination

A

Removal of unused/less active connections/synapses

46
Q

Amblyopia

A

“lazy” eye, brain ignored the lazy eye and the dominant eye takes over, Can be corrected with eyepatches

47
Q

Effect of enriching environments

A

Can affect neuronal populations and cause more connections between neurons

48
Q

Hubel and Wiesel kitten experiment

A

Sewed one eye of the kitten shut; found that the dominant eye will take over and discovered the sensitive period of visual development (in kitten)

49
Q
A