Chapter 2: Prenatal Development and Newborns Flashcards
Gamete
Sex cell (egg or sperm) with 23 chromosomes
Zygote
Combinations of both gametes, 46 chromosomes, grows via mitosis (cell division)
Day 4 of fetal development
The inner cell mass of the zygote is arranged into a hollow sphere (where identical twins split from)
End of week 1 of fetal development
The zygote has implanted into the uterine lining; differentiation begins
Week 2 of pregnancy
Inner cell mass of the zygote differentiates into three layers
After zygote has implanted into the uterine lining:
The neural tube is created, which eventually becomes the brain and spinal cord
Epigenesis
Aristotelian belief that the parts of the human body develop in succession
Cell migration
Movement of newly formed cells to a new location in the body/growing embryo
Cell differentiation
Embryonic stem cells specialize to become different cell types (underlying process unknown)
Apoptosis
Programmed cell death
Cephalocaudal Development
The areas of the fetus closer to the head form faster than those far from the head
Embryo at 4 weeks
Four folds in front head develops, primitive heart forms and pumps blood, arm and leg buds emerge
Embryo at 5.5 - 8.5 weeks
Nose, mouth, and palate differentiate (where cleft palate can form)
Fetus at 9 weeks
Rapid brain growth, all internal organs present, sexual differentiation occurs, eyes and ears forming, fingers and toes present
Fetus at 11 weeks
Heart develops to basic structure, spine and ribs are visible, major divisions of the brain form
Fetus at 16 weeks
Lower body growth accelerates, external genitals developed, fetal movement increases (primitive breathing motion)
Fetus at 18 weeks
Fine hair and greasy coating covers the body, facial expressions and sucking reflex can be observed
Fetus at 20 weeks
Oriented to head-down position, massive weight gain period
Fetus at 28 weeks
Triple in weight, brain and lungs fully developed, has reached the point of viability. Increased eye movement and neural activity. Auditory systems are developed and functioning
Placenta
Semipermeable defensive barrier for the fetus, provides hormones (progesterone and estrogen) and nutrients; can affect the baby and the mother
Hemochorial placenta
Inside the uterus; rewires the endometrium to reroute bloodflow to the baby, paralyzes the mothers arteries. Considered an ‘invasive’ placenta, which is comprised of fetal cells (that can become part of the mother’s organs forever)
Rates of miscarriage
1/3 pregnancies miscarry. 2/3 of that 33% occur before the pregnancy is even detectable. 25-50% of women experience a miscarriage. 6-15% of clinically recognized pregnancies end in miscarriage.
Non-genetic effects on prenatal development
Mother’s emotions, teratogens, mother’s health
O’Connor et. al. study
2002; Studied affects of maternal stress during pregnancy on behavior at 4 years old. Found a relationship between high stress levels and high behavioral issues. Many confounds (mental health, time gap, genetic predisposition to stress, socio-economic status, etc.)